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长寿与衰老领域的生物医学:对抗生物衰退的探索

Biomedicines in Longevity and Aging the Quest to Resist Biological Decline.

作者信息

Palmer Raymond D

机构信息

Spartan Therapeutics Dubai, United Arab Emirates.

出版信息

Biomedicine (Taipei). 2024 Mar 1;14(1):10-19. doi: 10.37796/2211-8039.1433. eCollection 2024.

Abstract

Aging is considered part of the natural process of life, however in recent years medical literature has started to show that specific facets of aging are beginning to be understood and those factors may even be considered preventable with various measures. Aging is also considered the number one cause of poor quality of life, disease, disability, and death, so the importance of understanding the aging process and how to control certain aspects of it cannot be underestimated when age related suffering is factored in. The causes of aging are now becoming well understood, and in recent years many therapies have already become available to the public to attenuate specific corridors of aging. The heterogeneity of the aging process and the biological drivers involved is examined here in parallel with various compounds and therapies to combat biological decline. The benefits for governments in keeping their populations healthy and vibrant are vast, and at the same time offer a great incentive to invest into newly emerging technologies that may prevent the onset of preventable disease. Whilst this paper only discusses nine pathways to the aging process, many more exist.

摘要

衰老被视为生命自然过程的一部分,然而近年来医学文献开始表明,衰老的特定方面正逐渐被理解,而且这些因素甚至可以通过各种措施加以预防。衰老也被认为是生活质量低下、疾病、残疾和死亡的首要原因,因此,当考虑到与年龄相关的痛苦时,理解衰老过程以及如何控制其某些方面的重要性不可低估。衰老的原因现在已被充分理解,近年来许多疗法已向公众提供,以减缓衰老的特定途径。本文将衰老过程的异质性以及相关的生物学驱动因素与各种对抗生物衰退的化合物和疗法一并进行探讨。政府保持民众健康和活力的益处巨大,同时也为投资新兴技术提供了强大动力,这些技术可能预防可预防疾病的发生。虽然本文仅讨论了九条衰老途径,但实际存在的途径更多。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/711a/10962562/4b786fb7421f/bmed-14-01-010f1.jpg

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