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动态干扰电流联合运动治疗对成人膝骨关节炎症状的疗效:一项随机对照临床试验。

Efficacy of diadynamic currents as an adjunct to exercise to manage symptoms of knee osteoarthritis in adults: A randomized controlled clinical trial.

机构信息

Department of Speech Therapy, Physical Therapy and Occupational Therapy, School of Medicine, São Paulo University, São Paulo, Brazil.

Centre for Pain Research, School of Health, Portland Building, Leeds Beckett University, Leeds, UK.

出版信息

Clin Rehabil. 2024 Jul;38(7):920-931. doi: 10.1177/02692155241236611. Epub 2024 Mar 27.

DOI:10.1177/02692155241236611
PMID:38533579
Abstract

OBJECTIVE

To investigate the effect of diadynamic currents administered prior to exercises on pain and disability in patients with osteoarthritis of the knee.

DESIGN

A randomized-controlled trial.

SETTING

Special Rehabilitation Services in Taboão da Serra.

PARTICIPANTS

Patients with bilateral knee osteoarthritis.

INTERVENTION

Participants were randomly allocated to Group I (diadynamic currents and exercises; n = 30, 60 knees) or Group II (exercises alone; n = 30, 60 knees) and were treated three times a week for 8 weeks.

MAIN OUTCOME MEASURES

The primary outcome measures were change in knee pain evaluated by visual analog scale and disability Index Score (Lequesne). Secondary outcomes included change in mobility (Timed Up and Go test), range of motion (goniometer), muscle strength (dynamometer), a composite score for pain and disability (Western Ontario and McMaster Universities Osteoarthritis questionnaire), and a drug diary to measure consumption of rescue pain medication (paracetamol). All measurements were collected at baseline, 8 weeks, and 6 months from baseline (follow-up).

RESULTS

There were 60 participants with a mean (SD) age of 63.40 (8.20) years. Between-group differences in the follow-up (8 weeks and 6 months) were observed for pain at rest, pain during activities of daily living and disability. There was improvement in Group I that was maintained for the three variables 6 months after treatment. Mean difference for pain at rest was -3.08 points (95% confidence interval -4.13; -2.02),  < 0.01 with an effect size of 1.4; mean difference for pain during activities of daily living was -2.40 points (95% confidence interval -3.34; -1.45),  < 0.01 with an effect size of 1.24; and mean difference for disability was -4.08 points (95% confidence interval -5.89; -2.26),  < 0.01 with an effect size of 1.04.

CONCLUSION

Patients with symptomatic knee osteoarthritis receiving 8 weeks of treatment with diadynamic currents as an adjunct to a program of exercises had significantly greater improvements in pain and disability than those receiving exercises alone. Beneficial effects were sustained for 6 months.

摘要

目的

探讨动态电流治疗对膝骨关节炎患者运动前疼痛和残疾的影响。

设计

随机对照试验。

地点

塔博恩达塞拉的特殊康复服务。

参与者

双侧膝骨关节炎患者。

干预措施

参与者被随机分配到 I 组(动态电流和运动;n = 30,60 膝)或 II 组(单独运动;n = 30,60 膝),每周治疗 3 次,共 8 周。

主要观察指标

主要观察指标为视觉模拟评分和残疾指数评分(Lequesne)评估的膝关节疼痛变化。次要结果包括活动能力(计时起立行走测试)、关节活动度(量角器)、肌肉力量(测力计)、疼痛和残疾综合评分(安大略西部和麦克马斯特大学骨关节炎问卷)以及测量止痛药(扑热息痛)消耗的药物日记。所有测量均在基线、8 周和 6 个月(随访)时进行。

结果

共有 60 名参与者,平均(SD)年龄为 63.40(8.20)岁。在随访(8 周和 6 个月)中,I 组在休息时疼痛、日常活动时疼痛和残疾方面存在组间差异。I 组的疼痛有所改善,且在治疗后 6 个月内保持了这三个变量。休息时疼痛的平均差异为-3.08 分(95%置信区间-4.13;-2.02),  < 0.01,效应量为 1.4;日常活动时疼痛的平均差异为-2.40 分(95%置信区间-3.34;-1.45),  < 0.01,效应量为 1.24;残疾的平均差异为-4.08 分(95%置信区间-5.89;-2.26),  < 0.01,效应量为 1.04。

结论

接受 8 周动态电流治疗联合运动方案治疗的症状性膝骨关节炎患者,疼痛和残疾改善明显优于单独运动组。有益效果持续 6 个月。

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