Department of Dermatology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Skin Res Technol. 2024 Apr;30(4):e13649. doi: 10.1111/srt.13649.
To establish accurate and objective dermoscopic diagnostic criteria and grading standards for males and females with androgenetic alopecia (AGA).
Twenty patients each with AGA, diffuse alopecia areata, telogen effluvium, and healthy controls were enrolled in the current study. In addition, 60 patients with grades F1/V1, F2/V2, and F3/V3 AGA (20 cases each) were enrolled. The patients underwent dermoscopic examinations. The sensitivity and specificity of the diagnostic criteria were based on the 60 AGA and 60 non-AGA. In addition, 150 patients diagnosed with AGA clinically and by dermoscopy were enrolled to calculate the accuracy of the grading criteria.
The diagnostic criteria included primary, secondary, and exclusion criteria. The grading criteria included three indices, which divided the severity of AGA into grades 1, 2, and 3. The sensitivity and specificity of the diagnostic criteria were 98.3% and 96.7% respectively. The accuracy of grade 1, 2, and 3 dermoscopic grading criteria were 96%, 92%, and 100% respectively, with a total accuracy of 96%.
To test the diagnostic and grading criteria, more patients need to be collected.
The dermoscopic diagnostic and grading criteria are objective with good accuracy, which could provide a reasonable basis for the early diagnosis, grading treatment, and improved prognosis for AGA.
建立雄激素性脱发（AGA）男性和女性准确客观的皮肤镜诊断标准和分级标准。
本研究纳入了 20 例 AGA 患者、弥漫性斑秃、休止期脱发和健康对照组。此外，还纳入了 60 例 F1/V1、F2/V2 和 F3/V3 级 AGA 患者（每组 20 例）。患者接受了皮肤镜检查。根据 60 例 AGA 和 60 例非 AGA 患者，确定了诊断标准的敏感性和特异性。此外，还纳入了 150 例经临床和皮肤镜检查诊断为 AGA 的患者，以计算分级标准的准确性。
诊断标准包括主要标准、次要标准和排除标准。分级标准包括 3 个指标，将 AGA 的严重程度分为 1 级、2 级和 3 级。诊断标准的敏感性和特异性分别为 98.3%和 96.7%。1 级、2 级和 3 级皮肤镜分级标准的准确性分别为 96%、92%和 100%，总准确性为 96%。
为了检验诊断和分级标准，需要收集更多的患者。
皮肤镜诊断和分级标准具有良好的准确性和客观性，可为 AGA 的早期诊断、分级治疗和改善预后提供合理依据。
