Univ Brest, CNRS, IRD, Ifremer, LEMAR, IUEM, F-29280 Plouzane, France.
Mar Drugs. 2024 Mar 5;22(3):121. doi: 10.3390/md22030121.
The effect of UV radiation on the accumulation of mycosporine-like amino acids (MAAs) and pigments was investigated on red macroalga cultivated for 21 days. The data were combined with the effect of NaNO to further investigate the synthesis of these nitrogenous compounds. A progressive decrease in both total MAA and pigment contents was observed, with a positive effect of nitrate supply. Usujirene was the only MAA exhibiting a significantly increasing content when exposed to UV radiation, changing from 9% to 24% of the total MAA's contribution, with no variation observed with NaNO. This suggests a specific induction or synthesis pathway of usujirene for photoprotection, while the synthesis of other MAAs could have been limited by an insufficient amount of UV radiation and/or irradiance. The photoprotective ability of some MAAs could have been impacted by nitrogen starvation over time, resulting in a limited synthesis and/or potential use of MAAs as a nitrogen source for red macroalgae. The data confirmed the multiple effects of environmental factors on the synthesis of MAAs while providing new insights into the specific synthesis of usujirene, which could find an application in the cosmetics sector as natural sunscreen or an anti-ageing agent.
研究了 21 天培养的红色大型藻类中紫外线辐射对菌 啉氨基酸（MAAs）和色素积累的影响。将数据与硝酸钠的影响相结合，进一步研究了这些含氮化合物的合成。观察到总 MAAs 和色素含量都呈渐进性下降，硝酸盐供应有积极影响。当暴露于紫外线辐射时，只有 Usujirene 表现出明显增加的含量，从总 MAAs 贡献的 9%增加到 24%，而与 NaNO 没有变化。这表明 Usujirene 存在一种特定的诱导或合成途径用于光保护，而其他 MAAs 的合成可能受到紫外线辐射和/或辐照度不足的限制。随着时间的推移，氮饥饿可能会影响一些 MAAs 的光保护能力，导致 MAAs 的合成有限，以及 MAAs 作为红色大型藻类氮源的潜在用途有限。这些数据证实了环境因素对 MAAs 合成的多种影响，同时为 Usujirene 的特定合成提供了新的见解，它可能在化妆品领域作为天然防晒霜或抗衰老剂得到应用。
