Systems Environmental Health and Energy Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.
Universidad San Ignacio de Loyola, Av. La Fontana 501, Lima 12 Lima, Peru.
Chemosphere. 2024 May;355:141760. doi: 10.1016/j.chemosphere.2024.141760. Epub 2024 Mar 25.
A significant and pressing issue revolves around the potential human exposure to endocrine disrupting chemicals (EDCs), which pose a substantial risk primarily through contaminated beverages. However, a comprehensive review for comparison of the migration rates of EDCs into these matrixes is currently lacking. This study reviews the beverages contamination with EDCs, including phthalates (PAEs), bisphenol A (BPA), hormone-like compounds, elements, and other organic EDCs. Also, the EDCs migration into milk and other dairy products, coffee, tea, and cold beverages related to their release from contact materials, preparation components, and storage conditions are briefly summarized. The data illustrates that besides the contamination of raw materials, the presence of EDCs associated with the type of food contact materials (FCMs)and their migration rate is increased with acidity, temperature, and storage time. The highest concentration of PAEs was detected from plastic and synthetic polymer films, while BPA strongly leaches from epoxy resins and canned metal. Furthermore, the presence of elements with endocrine disrupting characteristics was confirmed in cold beverages, soft drinks, hot drink and milk. Moreover, hormone-like compounds have been found to be released from coffee preparation components. Despite the few data about the migration rate of other EDCs including UV-stabilizers, surfactants, and antibacterial compounds into beverages, their presence was reported into milk, coffee, and different beverages, especially in packed samples. Studies on the EDCs leaching have primarily focused on PAEs and BPA, while other compounds require further investigation. Regardless, the possible risk that EDCs pose to humans through beverage consumption cannot be overlooked.
一个重要且紧迫的问题是,人类可能会接触到内分泌干扰化学物质(EDCs),这些化学物质主要通过受污染的饮料对人体造成极大的风险。然而,目前缺乏对这些基质中 EDCs 迁移率进行全面比较的综述。本研究综述了 EDCs 在饮料中的污染情况,包括邻苯二甲酸酯(PAEs)、双酚 A(BPA)、类激素化合物、元素和其他有机 EDCs。此外,还简要总结了 EDCs 从接触材料、制备成分和储存条件中迁移到牛奶和其他乳制品、咖啡、茶和冷饮中的情况。数据表明,除了原材料的污染外,与食品接触材料(FCMs)类型相关的 EDCs 的存在及其迁移率随着酸度、温度和储存时间的增加而增加。在塑料和合成聚合物薄膜中检测到最高浓度的 PAEs,而 BPA 则强烈地从环氧树脂和罐头金属中浸出。此外,在冷饮、软饮料、热饮和牛奶中也证实了具有内分泌干扰特征的元素的存在。此外,从咖啡制备成分中释放出了类激素化合物。尽管关于其他 EDCs(包括紫外线稳定剂、表面活性剂和抗菌化合物)迁移到饮料中的数据较少,但它们已被报道存在于牛奶、咖啡和各种饮料中,尤其是在包装样品中。EDCs 浸出的研究主要集中在 PAEs 和 BPA 上,而其他化合物则需要进一步研究。无论如何,通过饮用饮料对人类造成 EDCs 的潜在风险不容忽视。