Department of Basic Science, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Marine Pharmaceutical Science Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Int J Biol Macromol. 2024 May;266(Pt 1):131147. doi: 10.1016/j.ijbiomac.2024.131147. Epub 2024 Mar 26.
Seaweed, a diverse group of marine macroalgae, has emerged as a rich source of bioactive compounds with numerous health-promoting properties. Among these, phenolic compounds have garnered significant attention for their diverse therapeutic applications. This review examines the methodologies employed in the extraction and purification of phenolic compounds from seaweed, emphasizing their importance in unlocking the full potential of these oceanic treasures. The article provides a comprehensive overview of the structural diversity and biological activities of seaweed-derived phenolics, elucidating their antioxidant, anti-inflammatory, and anticancer properties. Furthermore, it explores the impact of extraction techniques, including conventional methods and modern green technologies, on the yield and quality of phenolic extracts. The purification strategies for isolating specific phenolic compounds are also discussed, shedding light on the challenges and advancements in this field. Additionally, the review highlights the potential applications of seaweed-derived phenolics in various industries, such as pharmaceuticals, cosmetics, and functional foods, underscoring the economic value of these compounds. Finally, future perspectives and research directions are proposed to encourage continued exploration of seaweed phenolics, fostering a deeper understanding of their therapeutic potential and promoting sustainable practices in the extraction and purification processes. This comprehensive review serves as a valuable resource for researchers, industry professionals, and policymakers interested in harnessing the untapped potential of phenolic compounds from seaweed for the betterment of human health and environmental sustainability.
海藻是一类多样化的海洋大型藻类，已成为具有多种促进健康特性的生物活性化合物的丰富来源。在这些化合物中，酚类化合物因其广泛的治疗应用而受到极大关注。本文综述了从海藻中提取和纯化酚类化合物的方法，强调了这些方法在挖掘这些海洋宝藏的全部潜力方面的重要性。文章全面概述了海藻衍生酚类化合物的结构多样性和生物活性，阐明了它们的抗氧化、抗炎和抗癌特性。此外，还探讨了提取技术（包括传统方法和现代绿色技术）对酚类提取物产量和质量的影响。还讨论了分离特定酚类化合物的纯化策略，揭示了该领域的挑战和进展。此外，本文还强调了海藻衍生酚类化合物在制药、化妆品和功能性食品等各个行业的潜在应用，突出了这些化合物的经济价值。最后，提出了未来的展望和研究方向，以鼓励继续探索海藻酚类化合物，加深对其治疗潜力的理解，并促进提取和纯化过程中的可持续实践。本综述为研究人员、行业专业人士和政策制定者提供了有价值的资源，他们有兴趣利用海藻酚类化合物的未开发潜力，促进人类健康和环境可持续性的发展。
