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超声在儿童鼻骨骨折诊断中的应用:系统评价和荟萃分析。

Diagnostic utility of ultrasound in pediatric nasal bone fractures: a systematic review and meta-analysis.

机构信息

Department of Radiology, Keck School of Medicine, University of Southern California (USC), 1441 Eastlake Ave Ste 2315, Los Angeles, CA, 90089, USA.

Department of Radiology, Mayo Clinic, Rochester, MN, USA.

出版信息

Emerg Radiol. 2024 Jun;31(3):417-428. doi: 10.1007/s10140-024-02225-1. Epub 2024 Mar 28.

Abstract

Ultrasonography, a radiation-free and cost-effective modality, stands out as a promising tool for evaluating nasal bone fractures. Despite limited literature on its pediatric application, there is an increasing recognition of its potential to enhance diagnostic precision. To evaluate the diagnostic efficacy of ultrasound in detecting pediatric nasal bone fractures. Employing established guidelines, a systematic review and meta-analysis were conducted through a comprehensive literature search in PubMed, Scopus, Web of Science, and Embase databases until December 5, 2023. Inclusion criteria encompassed studies reporting diagnostic accuracy measures of ultrasound in pediatric patients with nasal bone fractures. Data extraction and analysis were undertaken for the selected studies. Involving four studies with 277 patients, ultrasound demonstrated a pooled sensitivity of 66.1% (95% CI: 35.1-87.5%) and specificity of 86.8% (95% CI: 80.1-91.4%) in diagnosing pediatric nasal fractures. The area under the receiver operating characteristic curve (AUC) was 0.88 (95% CI: 0.72-0.93). After excluding an outlier study, sensitivity and specificity increased to 78.0% (95% CI: 65.6-86.9%) and 87.8 (95% CI: 78.1-93.6%), respectively, with an AUC of 0.79 (95% CI: 0.75-0.94). Pooled positive and negative likelihood ratios were 5.11 (95% CI: 2.12-9.15) and 0.40 (95% CI: 0.14-0.77) before exclusion and 6.75 (95% CI: 3.47-12.30) and 0.26 (95% CI: 0.15-0.40) after exclusion of an outlier study, respectively. This study highlighted ultrasonography's utility in diagnosing pediatric nasal bone fractures with high accuracy and specificity. However, caution is advised in relying solely on ultrasound due to suboptimal overall diagnostic performance, evident in likelihood ratios.

摘要

超声检查作为一种无辐射且具有成本效益的方法,在评估鼻骨骨折方面表现出很大的潜力。尽管其在儿科应用方面的文献有限,但人们越来越认识到它提高诊断准确性的潜力。为了评估超声检查在诊断儿科鼻骨骨折方面的诊断效果。采用既定的指南,通过对 PubMed、Scopus、Web of Science 和 Embase 数据库进行全面的文献检索,进行了系统评价和荟萃分析,检索时间截至 2023 年 12 月 5 日。纳入标准包括报告超声检查在儿科鼻骨骨折患者中诊断准确性测量的研究。对选定的研究进行数据提取和分析。涉及四项研究,共 277 例患者,超声检查诊断儿科鼻骨骨折的汇总敏感性为 66.1%(95%CI:35.1-87.5%),特异性为 86.8%(95%CI:80.1-91.4%)。受试者工作特征曲线下面积(AUC)为 0.88(95%CI:0.72-0.93)。排除异常值研究后,敏感性和特异性分别提高至 78.0%(95%CI:65.6-86.9%)和 87.8%(95%CI:78.1-93.6%),AUC 为 0.79(95%CI:0.75-0.94)。汇总阳性和阴性似然比分别为 5.11(95%CI:2.12-9.15)和 0.40(95%CI:0.14-0.77),排除异常值研究后分别为 6.75(95%CI:3.47-12.30)和 0.26(95%CI:0.15-0.40)。本研究强调了超声检查在诊断儿科鼻骨骨折方面的高准确性和特异性。然而,由于总体诊断性能不佳,似然比显示,在仅依赖超声检查时应谨慎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c64/11130032/eb0871144012/10140_2024_2225_Fig1_HTML.jpg

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