Department of Geriatric Medicine, Gazi University Faculty of Medicine, 06560, Ankara, Turkey.
Eur Geriatr Med. 2024 Aug;15(4):1023-1029. doi: 10.1007/s41999-024-00966-3. Epub 2024 Mar 28.
There is a need for an easily measurable and reliable surrogate marker for physical frailty. This study aims to investigate the predictive capacity of adductor pollicis muscle thickness (AMPT), which can be easily measured externally and minimally influenced by subcutaneous adipose tissue, for physical frailty.
A total of 589 patients (16.3% physically frail, 54.7% pre-frail, 29% robust) were included. Comprehensive geriatric assessments and anthropometric measurements of the patients were performed. APMT was assessed with a skinfold caliper. Physical frailty was diagnosed using the fried frailty phenotype. The predictive ability of APMT for the diagnosis of frailty was examined.
Of all the participants, 64.3% were women, and the average age was 74 ± 5.9 years. There was no significant difference in waist and hip circumference, or body mass index between the frail and non-frail groups. APMT, handgrip strength, gait speed, and calf circumference were significantly lower in frail patients than in non-frail ones (p < 0.01). The area under the curve (AUC) of APMT for physical frailty was determined to be 0.627 (95% confidence interval [CI] 0.58-0.66; p < 0.001). The best cut-off value for APMT was ≤ 18.5 mm for all individuals.
Adductor pollicis muscle thickness can be a useful anthropometric marker for evaluating the risk of physical frailty.
需要一种易于测量且可靠的身体虚弱的替代指标。本研究旨在探讨可通过外部轻易测量且受皮下脂肪组织影响较小的拇内收肌厚度（AMPT）对身体虚弱的预测能力。
共纳入 589 名患者（16.3%身体虚弱，54.7%虚弱前期，29%强健）。对患者进行全面的老年评估和人体测量学测量。使用皮褶卡尺评估 AMPT。使用 fried 虚弱表型诊断身体虚弱。检查了 AMPT 对虚弱诊断的预测能力。
所有参与者中，64.3%为女性，平均年龄为 74±5.9 岁。虚弱组和非虚弱组的腰围和臀围或体重指数无显著差异。虚弱患者的 AMPT、握力、步态速度和小腿围均显著低于非虚弱患者（p<0.01）。AMPT 对身体虚弱的曲线下面积（AUC）确定为 0.627（95%置信区间[CI] 0.58-0.66；p<0.001）。对于所有个体，AMPT 的最佳截断值为≤18.5mm。
拇内收肌厚度可以作为评估身体虚弱风险的有用人体测量学指标。
