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超声引导下肺复张对减少全身麻醉非心脏手术后肺不张的影响:一项随机对照试验的系统评价和荟萃分析

Effect of ultrasound-guided lung recruitment to reduce pulmonary atelectasis after non-cardiac surgery under general anesthesia: a systematic review and meta-analysis of randomized controlled trials.

作者信息

Liao Bucheng, Liao Wuhao, Yin Shuang, Liu Shujuan, Wu Xinhai

机构信息

Department of Anesthesiology, Peking University Shenzhen Hospital, No. 1120, Lianhua Street, Shenzhen, 518000, Guangdong, China.

Department of Anesthesiology, Shenzhen Hospital, Southern Medical University, No. 1333, Xinhu Street, Shenzhen, 518000, Guangdong, China.

出版信息

Perioper Med (Lond). 2024 Mar 27;13(1):23. doi: 10.1186/s13741-024-00379-7.

Abstract

BACKGROUND

At present, the application of bedside lung ultrasound is increasing gradually, but there is no relevant expert consensus or guidance for its evaluation in the field of perioperative anesthesia. Through this meta-analysis, we tried to determine the impact of ultrasound-guided lung recruitment maneuvers (LRM) on perioperative patients.

METHODS

We searched PubMed, Cochrane Library database, Embase, and Clinical Trials gov for the randomized controlled trials (RCTs) published up to December 31, 2022. The primary outcome was the incidence of postoperative atelectasis. Secondary outcomes included lung ultrasound score (LUS) and LUS of each part. A total of 443 patients were examined in nine randomized controlled trials.

RESULTS

The incidence of atelectasis after surgery in patients with ultrasound-guided LRM was less (RR 0.31; 95% CI 0.25-0.40; p < 0.05). The LUS (WMD - 6.24; 95% CI - 6.90-5.59; p < 0.05) and the LUS of each part (LUS in front lung region (WMD - 2.00; 95% CI - 2.49 to - 1.51; p < 0.05); LUS in lateral lung region (WMD - 2.50; 95% CI - 3.20 to - 1.80; p < 0.05); LUS in posterior lung region (WMD - 3.24; 95% CI - 4.23 to - 2.24; p < 0.05)) in patients with ultrasound-guided LRM were lower.

CONCLUSION

Ultrasound-guided lung recruitment maneuvers have been shown to be a promising approach for improving perioperative lung ventilation by increasing aeration while mitigating the development of atelectasis. In comparison to non-ultrasound-guided methods, this technique has exhibited superior effects.

摘要

背景

目前,床旁肺超声的应用逐渐增多,但在围手术期麻醉领域,对于其评估尚无相关专家共识或指导意见。通过这项荟萃分析,我们试图确定超声引导下的肺复张手法(LRM)对围手术期患者的影响。

方法

我们检索了截至2022年12月31日发表的随机对照试验(RCT),数据库包括PubMed、Cochrane图书馆数据库、Embase和Clinical Trials gov。主要结局是术后肺不张的发生率。次要结局包括肺超声评分(LUS)及各部位的LUS。9项随机对照试验共纳入443例患者。

结果

超声引导下LRM患者术后肺不张的发生率较低(RR 0.31;95% CI 0.25 - 0.40;p < 0.05)。超声引导下LRM患者的LUS(WMD - 6.24;95% CI - 6.90 - 5.59;p < 0.05)及各部位的LUS(肺前区LUS(WMD - 2.00;95% CI - 2.49至 - 1.51;p < 0.05);肺外侧区LUS(WMD - 2.50;95% CI - 3.20至 - 1.80;p < 0.05);肺后区LUS(WMD - 3.24;95% CI - 4.23至 - 2.24;p < 0.05))均较低。

结论

超声引导下的肺复张手法已被证明是一种有前景的方法,可以通过增加通气量同时减轻肺不张的发生来改善围手术期肺通气。与非超声引导方法相比,该技术显示出更好的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d1a/10967192/251024b21aaa/13741_2024_379_Fig1_HTML.jpg

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