Mawson A R
Med Hypotheses. 1985 Dec;18(4):387-98. doi: 10.1016/0306-9877(85)90106-9.
Recent studies indicate that clinically-active systemic lupus erythematosus (SLE) is uncommon in patients with end-stage renal disease undergoing long-term hemodialysis. Several lines of indirect evidence suggest that the dialysis procedure itself may be responsible for inducing remission; that SLE could reflect a toxicity reaction to excessive tissue levels of vitamin A; and that remission associated with dialysis may be due to a gradual reduction in vitamin A levels at the sites of SLE activity.
最近的研究表明，临床上有活动症状的系统性红斑狼疮（SLE）在接受长期血液透析的终末期肾病患者中并不常见。几条间接证据表明，透析过程本身可能是导致病情缓解的原因；系统性红斑狼疮可能反映了对组织中维生素A过量的毒性反应；而与透析相关的病情缓解可能是由于系统性红斑狼疮活动部位的维生素A水平逐渐降低。
