Luo Wang, Li Yiran, Chen Shiqi, Liang Yili, Liu Xueduan
School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, China.
Key Laboratory of Biometallurgy, Ministry of Education, Changsha 410083, China.
Microorganisms. 2024 Feb 20;12(3):422. doi: 10.3390/microorganisms12030422.
Bioleaching has gained significant attention as a cost-effective and environmentally friendly approach for extracting metals from low-grade ores and industrial byproducts. The application of acidophiles in bioleaching has been extensively studied. Among the various mechanisms leaching microorganisms utilize, quorum sensing (QS) is pivotal in regulating their life activities in response to population density. QS has been confirmed to regulate bioleaching, including cell morphology, community structure, biofilm formation, and cell metabolism. Potential applications of QS have also been proposed, such as increasing mineral leaching rates by adding signaling molecules. This review is helpful for comprehensively understanding the role of QS in bioleaching and promoting the practical application of QS-based strategies in bioleaching process optimization.
生物浸出作为一种从低品位矿石和工业副产品中提取金属的经济高效且环境友好的方法，已受到广泛关注。嗜酸菌在生物浸出中的应用已得到广泛研究。在浸出微生物利用的各种机制中，群体感应（QS）对于调节其响应种群密度的生命活动至关重要。已证实群体感应可调节生物浸出，包括细胞形态、群落结构、生物膜形成和细胞代谢。还提出了群体感应的潜在应用，例如通过添加信号分子提高矿物浸出率。这篇综述有助于全面理解群体感应在生物浸出中的作用，并促进基于群体感应的策略在生物浸出过程优化中的实际应用。
