Division of Natural and Applied Science, Duke Kunshan University, No. 8 Duke Avenue, Kunshan 215316, China.
Viruses. 2024 Mar 17;16(3):458. doi: 10.3390/v16030458.
Avian influenza viruses (AIVs) have posed a significant pandemic threat since their discovery. This review mainly focuses on the epidemiology, virology, pathogenesis, and treatments of avian influenza viruses. We delve into the global spread, past pandemics, clinical symptoms, severity, and immune response related to AIVs. The review also discusses various control measures, including antiviral drugs, vaccines, and potential future directions in influenza treatment and prevention. Lastly, by summarizing the insights from previous pandemic control, this review aims to direct effective strategies for managing future influenza pandemics.
禽流感病毒(AIVs)自发现以来一直构成重大的大流行威胁。本综述主要关注禽流感病毒的流行病学、病毒学、发病机制和治疗方法。我们深入探讨了 AIV 在全球的传播、过去的大流行、临床症状、严重程度和与 AIV 相关的免疫反应。该综述还讨论了各种控制措施,包括抗病毒药物、疫苗以及流感治疗和预防的潜在未来方向。最后,通过总结以往大流行控制的见解,本综述旨在为管理未来流感大流行提供有效的策略。