School of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Translational Medicine Center for Stem Cell Therapy & Institute for Regenerative Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
J Evid Based Integr Med. 2024 Jan-Dec;29:2515690X241241859. doi: 10.1177/2515690X241241859.
Pulse width, which can reflect , excess, and deficiency, has been used for diagnosing diseases and determining the prognosis in traditional Chinese medicine (TCM). This study aimed to devise an objective method to measure the pulse width based on an array pulse diagram for objective diagnosis.
The channel 6, the region wherein the pulse wave signal is the strongest, is located in the middle of the pulse sensor array and at the position of during data collection. Therefore, the main wave (h) time of the pulse wave was collected from the channel 6 through calculation. The left h time was collected from the remaining 11 channels. The amplitudes at these time points were extracted as the h amplitudes for each channel. However, the pulse width could not be calculated accurately at 12 points. Consequently, a bioharmonic spline interpolation algorithm was used to interpolate the h amplitude data obtained from the horizontal and vertical points, yielding 651 (31 × 21) h amplitude data. The 651 data points were converted into a heat map to intuitively calculate the pulse width. The pulse width was calculated by multiplying the number of grids on the vertical axis with the unit length of the grid. The pulse width was determined by TCM doctors to verify the pulse width measurement accuracy. Meanwhile, a color Doppler ultrasound examination of the volunteers' radial arteries was performed and the intravascular meridian widths of the radial artery compared with the calculated pulse widths to determine the reliability.
The pulse width determined using the maximal h amplitude method was comparable with the radial artery intravascular meridian widths measured using color Doppler ultrasound. The h amplitude was higher in the high blood pressure group and the pulse width was greater.
The pulse width determined using the maximal h amplitude was objective and accurate. Comparison between the pulse widths of the normal and high blood pressure groups verified the reliability of the method.
脉宽可反映人体气血的盛衰，在中医中被用于诊断疾病和判断预后。本研究旨在设计一种基于脉象图阵列的客观测量脉宽的方法，实现客观诊断。
在数据采集时，通道 6 位于传感器阵列的中间位置，是脉搏波信号最强的部位，即 位置，通过计算可以得到主波（h）的时间。从通道 6 中采集左 h 时间，从其余 11 个通道中采集左 h 时间。提取这些时间点的幅度作为每个通道的 h 幅度。然而，在 12 个点无法准确计算脉宽。因此，采用生物谐波样条插值算法对水平和垂直点的 h 幅度数据进行插值，得到 651 个（31×21）h 幅度数据。将 651 个数据点转换为热图，直观地计算脉宽。脉宽通过乘以垂直轴上的网格数与网格的单位长度计算得出。由中医医生判断脉宽测量的准确性，并验证。同时，对志愿者桡动脉进行彩色多普勒超声检查，比较桡动脉血管内经脉宽度与计算出的脉宽，以确定其可靠性。
采用最大 h 幅度法确定的脉宽与彩色多普勒超声测量的桡动脉血管内经脉宽度具有可比性。高血压组的 h 幅度较高，脉宽较大。
采用最大 h 幅度法确定的脉宽客观准确。正常组和高血压组脉宽的比较验证了该方法的可靠性。
