Youn Linda, Srinivasan Mirra, Kuta Amber, Barnard Jacyln, Khalil Mazen
Internal Medicine, St. Bernards Medical Center, Jonesboro, USA.
Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Cureus. 2024 Feb 26;16(2):e54967. doi: 10.7759/cureus.54967. eCollection 2024 Feb.
Non-small cell lung cancer metastasis to skeletal muscle is an uncommon occurrence. Lung cancers are more likely to spread to the brain, bone, liver, and adrenals. Here, we present a rare case of non-small cell lung cancer metastasis to the skeletal muscle in a 54-year-old male. In addition, we present a literature review on skeletal metastasis of non-small cell lung cancer. The most frequent presentation of skeletal muscle metastasis is muscular pain with or without swelling. The mechanism of metastasis to muscle is not well understood; it is theorized that hematogenous spread is the most likely route. As with our patient, the presence of skeletal muscle mass is considered an aggressive disease with poor survival, usually less than one year. The treatment for muscle metastasis is often palliative in the form of radiation therapy, chemotherapy, or surgical removal of the mass.
非小细胞肺癌转移至骨骼肌是一种罕见的情况。肺癌更有可能扩散至脑、骨、肝和肾上腺。在此，我们报告一例54岁男性非小细胞肺癌转移至骨骼肌的罕见病例。此外，我们还对非小细胞肺癌的骨骼转移进行了文献综述。骨骼肌转移最常见的表现是伴有或不伴有肿胀的肌肉疼痛。转移至肌肉的机制尚不完全清楚；据推测，血行播散是最可能的途径。与我们的患者一样，存在骨骼肌肿块被认为是一种侵袭性疾病，生存率低，通常不到一年。肌肉转移的治疗通常采用姑息治疗，形式包括放射治疗、化疗或手术切除肿块。
