Ali Mostafa A, Amirthalingam Palanisamy, Veeramani Vinoth-Prabhu, Alasiri Abdulmajeed M, Alsalimi Meshal N, Alatawi Fahad, Albalawi Mutlaq M
Pharmacy Practice Department, Faculty of Pharmacy, University of Tabuk, Tabuk, SAU.
Department of Clinical Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, EGY.
Cureus. 2024 Feb 26;16(2):e54927. doi: 10.7759/cureus.54927. eCollection 2024 Feb.
Mental health disorders are often chronic and disabling conditions that impact different populations, irrespective of age, cultural background, or socioeconomic status. This study aimed to describe the prescribing pattern of psychotropic medications in patients with psychiatric disorders.
This research was a retrospective investigation of psychotropic medication prescribing patterns and conducted at Eradah Mental Health Hospital at Tabuk City, Saudi Arabia. The data were extracted from the electronic medical database of adult patients presenting to the outpatient and inpatient clinics of a mental health hospital between 2020 and 2023. The diagnosis of psychiatric disorders was identified using the International Classification of Diseases 10th Revision (ICD-10) codes version 2019 for mental and behavioral disorders (F00 to F99).
The electronic medication records of 526 patients were reviewed, of whom 510 (97%) were Saudi nationals, 368 (69.9%) were males, 235 (44.7%) were between 31 and 40 years of age, and 233 (44.3%) were outpatients. The most common psychiatric diagnoses were schizophrenia (33.3%), followed by bipolar affective disorder (16.9%). A total of 2,153 medication orders for psychotropic medications were quantified. Second-generation antipsychotics (SGAs) and first-generation antipsychotics (FGAs) were the top prescribed medication classes (1,290, 60%), followed by mood stabilizers (324, 15%). More than one-half of the patients (282, 53.6%) received a combination of antipsychotic and mood stabilizers, and 155 (29.5%) received a combination of antipsychotic and antidepressant medications. No significant differences were observed in prescribing for males and females.
Schizophrenia was highly prevalent among adult patients who sought mental healthcare. Polypharmacy of psychotropic medication was common depending on the symptoms' severity and comorbid psychiatric diseases.
精神健康障碍通常是慢性致残性疾病，会影响不同人群，无论其年龄、文化背景或社会经济地位如何。本研究旨在描述精神疾病患者精神药物的处方模式。
本研究是对精神药物处方模式的回顾性调查，在沙特阿拉伯塔布克市的埃拉达心理健康医院进行。数据从2020年至2023年期间到一家心理健康医院门诊和住院部就诊的成年患者的电子医疗数据库中提取。使用2019版《国际疾病分类第10次修订本》（ICD-10）中精神和行为障碍（F00至F99）的编码来确定精神疾病的诊断。
对526例患者的电子用药记录进行了审查，其中510例（97%）为沙特国民，368例（69.9%）为男性，235例（44.7%）年龄在31至40岁之间，233例（44.3%）为门诊患者。最常见的精神疾病诊断是精神分裂症（33.3%），其次是双相情感障碍（16.9%）。共量化了2153份精神药物处方。第二代抗精神病药物（SGA）和第一代抗精神病药物（FGA）是处方量最多的药物类别（1290份，60%），其次是心境稳定剂（324份，15%）。超过一半的患者（282例，53.6%）接受了抗精神病药物和心境稳定剂的联合用药，155例（29.5%）接受了抗精神病药物和抗抑郁药物的联合用药。男性和女性在处方方面未观察到显著差异。
精神分裂症在寻求心理治疗的成年患者中非常普遍。根据症状严重程度和合并的精神疾病，精神药物的联合用药很常见。
