Garza Nicholas J, Arulmozhi Kavitha, LePhong Christopher, Titapiwatanakun Ruetima, Fernandez Karen S
Pediatrics, Valley Children's Healthcare, Madera, USA.
Pathology and Laboratory Medicine, Valley Children's Healthcare, Madera, USA.
Cureus. 2024 Feb 26;16(2):e54974. doi: 10.7759/cureus.54974. eCollection 2024 Feb.
Paraneoplastic presentations are often the initial presenting symptom of a malignant process. A 15-year-old female presented with a progressively growing, sclerotic lesion of the neck restricting the range of motion. She was found to have bilateral ovarian tumors that proved to be diffuse large B-cell lymphoma (DLBCL). After starting cyclophosphamide, vincristine, and prednisone (COP), she had a rapid and complete resolution of the sclerotic lesion, as well as a favorable response to the neoplastic process. In this report, we present a very rare case of extranodal lymphoma associated with a paraneoplastic skin lesion.
副肿瘤表现通常是恶性疾病的首发症状。一名15岁女性因颈部出现逐渐增大的硬化性病变,限制了活动范围而就诊。她被发现患有双侧卵巢肿瘤,病理证实为弥漫性大B细胞淋巴瘤(DLBCL)。在开始使用环磷酰胺、长春新碱和泼尼松(COP)治疗后,她颈部的硬化性病变迅速完全消退,并且对肿瘤性疾病也有良好反应。在本报告中,我们呈现了一例非常罕见的结外淋巴瘤伴副肿瘤性皮肤病变的病例。