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Sertoli cells are the source of stem cell factor for spermatogenesis.支持细胞是精子发生中干细胞因子的来源。
Development. 2023 Mar 15;150(6). doi: 10.1242/dev.200706. Epub 2023 Mar 20.
2
Heat stress disrupts spermatogenesis via modulation of sperm-specific calcium channels in rats.热应激通过调节大鼠精子特异性钙通道破坏精子发生。
J Therm Biol. 2023 Feb;112:103465. doi: 10.1016/j.jtherbio.2023.103465. Epub 2023 Jan 9.
3
Arachidonic acid impairs the function of the blood-testis barrier via triggering mitochondrial complex-ROS-P38 MAPK axis in hyperthermal Sertoli cells.花生四烯酸通过触发高热环境下睾丸支持细胞中线粒体复合物-ROS-P38MAPK 轴来损害血睾屏障的功能。
Ecotoxicol Environ Saf. 2023 Mar 1;252:114598. doi: 10.1016/j.ecoenv.2023.114598. Epub 2023 Feb 10.
4
NGF regulates sertoli cell growth and prevents LPS-induced junction protein damage via PI3K/AKT/NFκB signaling.神经生长因子通过PI3K/AKT/NFκB信号通路调节支持细胞生长并防止脂多糖诱导的连接蛋白损伤。
Theriogenology. 2023 Jan 1;195:138-148. doi: 10.1016/j.theriogenology.2022.10.017. Epub 2022 Oct 18.
5
Sertoli Cell-Germ Cell Interactions Within the Niche: Paracrine and Juxtacrine Molecular Communications.生精细胞-支持细胞相互作用在小生境内:旁分泌和接触依赖性分子通讯。
Front Endocrinol (Lausanne). 2022 Jun 10;13:897062. doi: 10.3389/fendo.2022.897062. eCollection 2022.
6
Association of decreased sperm motility and increased seminal plasma IGF-I, IGF-II, IGFBP-2, and PSA levels in infertile men.不育男性精子活动力降低与精液 IGF-I、IGF-II、IGFBP-2 和 PSA 水平升高有关。
Endocrine. 2021 Dec;74(3):698-706. doi: 10.1007/s12020-021-02823-w. Epub 2021 Jul 17.
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Sertoli cells as key drivers of testis function.支持细胞作为睾丸功能的关键驱动因素。
Semin Cell Dev Biol. 2022 Jan;121:2-9. doi: 10.1016/j.semcdb.2021.06.016. Epub 2021 Jul 3.
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Chronic scrotal hyperthermia induces azoospermia and severe damage to testicular tissue in mice.慢性阴囊高温会导致小鼠不育和睾丸组织严重损伤。
Acta Histochem. 2021 May;123(4):151712. doi: 10.1016/j.acthis.2021.151712. Epub 2021 Apr 10.
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The role of different compounds on the integrity of blood-testis barrier: A concise review based on in vitro and in vivo studies.不同化合物对血睾屏障完整性的作用:基于体外和体内研究的简要综述。
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盆腔MRI对子宫内膜异位症的诊断价值与手术结果的比较:一项横断面研究。

Evaluation of diagnostic value of pelvic MRI in endometriosis in comparison with surgical findings: A cross-sectional study.

作者信息

Nafisi Moghadam Reza, Tamizi Fatemeh, Kazem Razavi Ratki Seid, Nafisi Moghadam Amin, Javaheri Atiyeh, Namiranian Nasim

机构信息

Department of Radiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Faculty of Medicine, Aliebnabitaleb Azad University, Yazd, Iran.

出版信息

Int J Reprod Biomed. 2024 Feb 23;22(1):55-60. doi: 10.18502/ijrm.v22i1.15242. eCollection 2024 Jan.

DOI:10.18502/ijrm.v22i1.15242
PMID:38544666
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10963879/
Abstract

BACKGROUND

Endometriosis is a multifocal gynecologic disorder during the fertility period in women. Magnetic resonance imaging (MRI) is an important diagnostic modality for this disease and can either be used alone or along with transvaginal ultrasonography.

OBJECTIVE

This study aims to compare the accuracy of pelvis MRI in pelvic deep endometriosis with laparoscopic findings in women referred to Shahid Sadoughi hospital in one year.

MATERIALS AND METHODS

This cross-sectional study was conducted on 40 women suspicious of endometriosis who referred to Shahid Sadoughi hospital, Yazd, Iran from November 2020-2021. Based on clinical findings and history, participants were referred to the imaging center for pelvic MRI. Finally, the results of MRI and diagnostic laparoscopy were compared with pathologic findings.

RESULTS

The sensitivity and specificity of MRI for pelvic endometriosis were 94.8% and 20%, respectively. Also, the positive predictive value and negative predictive value of MRI were 90.2% and 33.3%, respectively.

CONCLUSION

Laparoscopy is still the gold standard of endometriosis diagnosis, but MRI with susceptibility-weighted imaging sequence is the best noninvasive diagnostic method.

摘要

背景

子宫内膜异位症是育龄期女性的一种多灶性妇科疾病。磁共振成像(MRI)是诊断该疾病的一种重要方式,可单独使用或与经阴道超声检查联合使用。

目的

本研究旨在比较盆腔MRI诊断盆腔深部子宫内膜异位症的准确性与一年内转诊至沙希德·萨杜基医院的女性患者腹腔镜检查结果。

材料与方法

本横断面研究对2020年11月至2021年转诊至伊朗亚兹德沙希德·萨杜基医院的40例疑似子宫内膜异位症女性患者进行。根据临床表现和病史,将参与者转诊至影像中心进行盆腔MRI检查。最后,将MRI结果和诊断性腹腔镜检查结果与病理结果进行比较。

结果

MRI诊断盆腔子宫内膜异位症的敏感性和特异性分别为94.8%和20%。此外,MRI的阳性预测值和阴性预测值分别为90.2%和33.3%。

结论

腹腔镜检查仍是子宫内膜异位症诊断的金标准,但采用磁敏感加权成像序列的MRI是最佳的非侵入性诊断方法。