Qian Juan, Wang Xuesong
Juan Qian, Department of Orthopedics, Affiliated Hospital of Jiangnan University, 1000 Hefeng Road, Wuxi City, Jiangsu Province 214000, China.
Xuesong Wang, Department of Orthopedics, Affiliated Hospital of Jiangnan University, 1000 Hefeng Road, Wuxi City, Jiangsu Province 214000, China.
Pak J Med Sci. 2024 Mar-Apr;40(4):657-662. doi: 10.12669/pjms.40.4.8979.
To explore the risk factors of chronic pain after total knee arthroplasty (TKA) and to establish and verify a prediction model.
As a retrospective observational study, medical records of 239 patients who underwent TKA in Affiliated Hospital of Jiangnan University from January 2020 to December 2022 were reviewed. Fifty four patients suffered from chronic pain after TKA surgery. Univariate and multivariate logistic regression were used to analyze factors associated with the occurrence of chronic pain after TKA. A nomogram prediction model was established based on the identified independent risk factors, and its predictive effectiveness was evaluated.
Gender, postoperative 24-hourss numerical rating scale (NRS) and postoperative three months Hospital for Special Surgery Knee-Rating (HSS) scores were independent risk factors for chronic pain after TKA (<0.05). The area of the receiver operating characteristic (ROC) of the nomogram model based on these factors was 0.904 (95% confidence interval [CI): 0.861-0.947), which indicates a good predictive value for the postoperative chronic pain. When the optimal cut off value was selected, the sensitivity and specificity of the model were 92.6% and 74.1%, respectively, indicating that the predictive model is effective.
Gender, postoperative 24-hours NRS and postoperative three months HSS score are independent risk factors for chronic pain after TKA. The nomogram prediction model based on these factors is effective and can provide auxiliary reference for patients with chronic pain after TKA.
探讨全膝关节置换术(TKA)后慢性疼痛的危险因素,并建立和验证预测模型。
作为一项回顾性观察研究,回顾了2020年1月至2022年12月在江南大学附属医院接受TKA的239例患者的病历。54例患者在TKA手术后出现慢性疼痛。采用单因素和多因素逻辑回归分析TKA后慢性疼痛发生的相关因素。基于确定的独立危险因素建立列线图预测模型,并评估其预测效能。
性别、术后24小时数字评定量表(NRS)评分及术后3个月特种外科医院膝关节评分(HSS)是TKA后慢性疼痛的独立危险因素(P<0.05)。基于这些因素的列线图模型的受试者操作特征曲线(ROC)面积为0.904(95%置信区间[CI]:0.861-0.947),表明对术后慢性疼痛具有良好的预测价值。选择最佳截断值时,模型的敏感性和特异性分别为92.6%和74.1%,表明预测模型有效。
性别、术后24小时NRS评分及术后3个月HSS评分是TKA后慢性疼痛的独立危险因素。基于这些因素的列线图预测模型有效,可为TKA后慢性疼痛患者提供辅助参考。