Su Jialin, Li Meifang, Lin Yongping, Xiong Liu, Yuan Caixing, Zhou Zhimin, Yan Kunlong
School of Optoelectronic and Communication Engineering, Xiamen University of Technology, Xiamen, China.
Department of Medical Imaging, Affiliated Hospital of Putian University, Putian, China.
Quant Imaging Med Surg. 2024 Mar 15;14(3):2240-2254. doi: 10.21037/qims-23-1273. Epub 2024 Mar 7.
Computed tomography (CT) chest scans have become commonly used in clinical diagnosis. Image quality assessment (IQA) for CT images plays an important role in CT examination. It is worth noting that IQA is still a manual and subjective process, and even experienced radiologists make mistakes due to human limitations (fatigue, perceptual biases, and cognitive biases). There are also kinds of biases because of poor consensus among radiologists. Excellent IQA methods can reliably give an objective evaluation result and also reduce the workload of radiologists. This study proposes a deep learning (DL)-based automatic IQA method, to assess whether the image quality of respiratory phase on CT chest images are optimal or not, so that the CT chest images can be used in the patient's physical condition assessment.
This retrospective study analysed 212 patients' chest CT images, with 188 patients allocated to a training set (150 patients), validation set (18 patients), and a test set (20 patients). The remaining 24 patients were used for the observer study. Data augmentation methods were applied to address the problem of insufficient data. The DL-based IQA method combines image selection, tracheal carina segmentation, and bronchial beam detection. To automatically select the CT image containing the tracheal carina, an image selection model was employed. Afterward, the area-based approach and score-based approach were proposed and used to further optimize the tracheal carina segmentation and bronchial beam detection results, respectively. Finally, the score about the image quality of the patient's respiratory phase images given by the DL-based automatic IQA method was compared with the mean opinion score (MOS) given in the observer study, in which four blinded experienced radiologists took part.
The DL-based automatic IQA method achieved good performance in assessing the image quality of the respiratory phase images. For the CT sequence of the same patient, the DL-based IQA method had an accuracy of 92% in the assessment score, while the radiologists had an accuracy of 88%. The Kappa value of the assessment score between the DL-based IQA method and radiologists was 0.75, with a sensitivity of 85%, specificity of 91%, positive predictive value (PPV) of 92%, negative predictive value (NPV) of 93%, and accuracy of 88%.
This study develops and validates a DL-based automatic IQA method for the respiratory phase on CT chest images. The performance of this method surpassed that of the experienced radiologists on the independent test set used in this study. In clinical practice, it is possible to reduce the workload of radiologists and minimize errors caused by human limitations.
胸部计算机断层扫描(CT)已在临床诊断中广泛应用。CT图像的质量评估(IQA)在CT检查中起着重要作用。值得注意的是,IQA仍然是一个人工的主观过程,即使是经验丰富的放射科医生也会由于人类局限性(疲劳、感知偏差和认知偏差)而犯错。此外,由于放射科医生之间缺乏共识,还存在各种偏差。优秀的IQA方法能够可靠地给出客观评估结果,同时减少放射科医生的工作量。本研究提出一种基于深度学习(DL)的自动IQA方法,用于评估胸部CT图像呼吸期的图像质量是否最佳,以便胸部CT图像能够用于患者身体状况评估。
这项回顾性研究分析了212例患者的胸部CT图像,其中188例患者被分配到训练集(150例患者)、验证集(18例患者)和测试集(20例患者)。其余24例患者用于观察者研究。采用数据增强方法解决数据不足的问题。基于DL的IQA方法结合了图像选择、气管隆突分割和支气管束检测。为自动选择包含气管隆突的CT图像,采用了图像选择模型。随后,分别提出基于区域的方法和基于分数的方法,用于进一步优化气管隆突分割和支气管束检测结果。最后,将基于DL的自动IQA方法给出的患者呼吸期图像质量分数与观察者研究中给出的平均意见得分(MOS)进行比较,观察者研究中有四名经验丰富的放射科医生参与且均不知情。
基于DL的自动IQA方法在评估呼吸期图像质量方面表现良好。对于同一患者的CT序列,基于DL的IQA方法评估分数的准确率为92%,而放射科医生的准确率为88%。基于DL的IQA方法与放射科医生评估分数的Kappa值为0.75,敏感性为85%,特异性为91%,阳性预测值(PPV)为92%,阴性预测值(NPV)为93%,准确率为88%。
本研究开发并验证了一种基于DL的胸部CT图像呼吸期自动IQA方法。该方法在本研究使用的独立测试集上的表现超过了经验丰富的放射科医生。在临床实践中,有可能减少放射科医生的工作量,并将人类局限性导致的错误降至最低。