Ahmad Rawand E, Barakat Muna
Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman, 11931, Jordan.
Heliyon. 2024 Mar 15;10(6):e28028. doi: 10.1016/j.heliyon.2024.e28028. eCollection 2024 Mar 30.
This study investigates the dispensing patterns and knowledge of community pharmacists regarding Deanxit®, a combination of melitracen and flupentixol approved for the treatment of depression and anxiety in Jordan.
This study employed a mixed-methods approach, involving 75 randomly selected pharmacies in two Jordanian governorates (Amman and Irbid). The investigation involved simulated patient scenarios and structured interviews employing a validated tool.
The analysis revealed that 70.6% of pharmacists were willing to dispense Deanxit® based on simulated scenarios, indicating malpractice. The mean practice score was 0.5867 out of 18, underlining a substantial level of malpractice. Pharmacists demonstrated poor knowledge, with a median score of 2.0 out of 15, reflecting a lack of awareness about Deanxit's labeled indications. Furthermore, 96% reported dispensing without prescriptions, and 62.1% acknowledged encountering cases of improper Deanxit® use.
This study provides valuable insights into the current landscape of Deanxit® dispensing patterns, pharmacists' poor knowledge levels, and malpractices in Jordan. By identifying areas for improvement and offering recommendations for intervention, this study contributes to enhancing pharmacy practice and patient care outcomes in the region.
本研究调查了约旦社区药剂师关于黛力新(Deanxit®)的配药模式和知识,黛力新是美利曲辛和氟哌噻吨的复方制剂,已获批用于治疗抑郁症和焦虑症。
本研究采用混合方法,涉及约旦两个省份(安曼和伊尔比德)随机选取的75家药店。调查包括模拟患者场景和使用经过验证的工具进行结构化访谈。
分析显示,基于模拟场景,70.6%的药剂师愿意配发黛力新,这表明存在不当行为。实践平均得分在18分中为0.5867分,突出了相当程度的不当行为。药剂师知识水平较差,在15分中中位数得分为2.0分,反映出对黛力新标注适应症缺乏认识。此外,96%的人报告无处方配发,62.1%承认遇到过黛力新使用不当的病例。
本研究为约旦黛力新的配药模式、药剂师知识水平低下和不当行为的现状提供了有价值的见解。通过确定改进领域并提供干预建议,本研究有助于改善该地区的药学实践和患者护理结果。