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锂中毒:一例导致三度心脏传导阻滞的中毒病例报告。

Lithium Toxicity: A Case Report of Toxicity Resulting in a Third-degree Heart Block.

作者信息

Gaetani Samantha L, Amaducci Alexandra M, Fikse Derek, Koons Andrew L

机构信息

Lehigh Valley Health Network/University of South Florida Morsani College of Medicine, Department of Emergency and Hospital Medicine, Allentown, Pennsylvania.

Lehigh Valley Health Network/University of South Florida Morsani College of Medicine, Department of Emergency and Hospital Medicine, Division of Medical Toxicology, Allentown, Pennsylvania.

出版信息

Clin Pract Cases Emerg Med. 2024 Feb;8(1):53-56. doi: 10.5811/cpcem.1442.

Abstract

INTRODUCTION

Lithium is a medication used to treat bipolar disorder. It has a narrow therapeutic index, which frequently causes toxicity in patients.

CASE REPORT

We present an unusual case of a 66-year-old female with a history of bipolar disorder on chronic lithium, who developed a third-degree heart block, encephalopathy, and acute renal failure because of lithium toxicity.

CONCLUSION

This case highlights a rare but life-threatening case of complete heart block in the setting of lithium toxicity. The patient was treated with hemodialysis and pacemaker placement.

摘要

引言

锂是一种用于治疗双相情感障碍的药物。其治疗指数狭窄,常导致患者中毒。

病例报告

我们报告一例不寻常的病例,一名66岁患有双相情感障碍且长期服用锂盐的女性,因锂中毒出现三度房室传导阻滞、脑病和急性肾衰竭。

结论

该病例突出了锂中毒情况下罕见但危及生命的完全性心脏传导阻滞病例。患者接受了血液透析和起搏器植入治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59b2/10966491/6c7b161818aa/cpcem-8-53-g001.jpg

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