Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Med Oncol. 2024 Mar 28;41(5):102. doi: 10.1007/s12032-024-02345-1.
Extensive research has been conducted on the correlation between viral infections and hematological cancers ever since the identification of the Rous Sarcoma Virus as a cancer-causing agent. Numerous viruses, such as the Epstein-Barr virus, hepatitis B virus, hepatitis C virus, human immunodeficiency virus, human T-lymphotropic virus 1, and severe acute respiratory syndrome-related coronavirus 2, have been identified as potential contributors to the development and progression of cancer by disrupting normal cellular processes. Different viruses are associated with distinct forms of blood cancers, each exhibiting unique infection mechanisms, pathogenesis, and clinical symptoms. Understanding these connections is crucial for the development of effective prevention and treatment strategies. Healthcare professionals who possess a solid understanding of these associations can offer precise treatments and closely monitor potential complications in individuals with blood cancers and viral infections. By leveraging this information, healthcare providers can optimize patient care and improve outcomes for those affected by both viral infections and hematological cancers.
自 Rous 肉瘤病毒被确定为致癌剂以来,人们对病毒感染与血液系统癌症之间的相关性进行了广泛的研究。许多病毒,如 Epstein-Barr 病毒、乙型肝炎病毒、丙型肝炎病毒、人类免疫缺陷病毒、人类 T 淋巴细胞白血病病毒 1 型和严重急性呼吸综合征相关冠状病毒 2 型,通过破坏正常细胞过程,被认为是导致癌症发生和发展的潜在因素。不同的病毒与不同类型的血液癌症相关,每种病毒都具有独特的感染机制、发病机制和临床症状。了解这些关联对于制定有效的预防和治疗策略至关重要。对这些关联有深入了解的医疗保健专业人员可以为血液癌症和病毒感染患者提供精确的治疗,并密切监测潜在的并发症。通过利用这些信息,医疗保健提供者可以优化患者护理,改善受病毒感染和血液系统癌症影响的患者的预后。