Division of Interventional Radiology, Department of Radiology, UCLA Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Division of Liver and Pancreas Transplant Surgery, Department of Surgery, UCLA Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Department of Anesthesiology, UCLA Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Clin Liver Dis. 2024 May;28(2):317-329. doi: 10.1016/j.cld.2024.01.008. Epub 2024 Feb 10.
Hepatic encephalopathy (HE) is a clinically severe and devastating complication of decompensated liver disease affecting mortality, quality of life for patients and families, hospital admission rates, and overall health-care costs globally. Depending on the cause of HE, several medical treatment options have been developed and become available. In some refractory HE, such as spontaneous portosystemic shunt-related HE (SPSS-HE) or posttransjugular intrahepatic portosystemic shunt HE (post-TIPS HE), advanced interventional radiology (IR) procedures have been used, and shown to be effective in these conditions. This review presents 2 effective IR procedures for managing SPSS-HE and post-TIPS HE.
肝性脑病(HE)是一种严重的临床并发症,影响失代偿性肝病患者的死亡率、生活质量以及家庭,还会导致全球住院率和整体医疗保健费用上升。根据 HE 的病因,已经开发并提供了几种医疗治疗选择。在一些难治性 HE 中,如自发性门体分流相关 HE(SPSS-HE)或经颈静脉肝内门体分流术相关 HE(post-TIPS HE),已经使用了先进的介入放射学(IR)程序,并且在这些情况下显示出有效。这篇综述介绍了两种有效的 IR 程序,用于治疗 SPSS-HE 和 post-TIPS HE。