Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, VA, USA; Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Med Clin North Am. 2024 May;108(3):581-594. doi: 10.1016/j.mcna.2023.12.004. Epub 2024 Jan 4.
The number of older adults age ≥75 with chronic coronary disease (CCD) continues to rise. CCD is a major contributor to morbidity, mortality, and disability in older adults. Older adults are underrepresented in randomized controlled trials of CCD, which limits generalizability to older adults living with multiple chronic conditions and geriatric syndromes. This review discusses the presentation of CCD in older adults, reviews the guideline-directed medical and invasive therapies, and recommends a patient-centric approach to making treatment decisions.
≥75 岁的老年慢性冠状动脉疾病(CCD)患者人数持续增加。CCD 是导致老年人发病率、死亡率和残疾的主要原因。老年人在 CCD 的随机对照试验中代表性不足,这限制了将其推广应用于患有多种慢性疾病和老年综合征的老年人。本综述讨论了老年 CCD 的表现,回顾了指南指导的医学和介入治疗,并建议采取以患者为中心的方法来做出治疗决策。