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中国 HIV 阴性/未知的男男性行为者预期 HIV 污名的特征和影响因素:回归混合模型。

Characteristics and influencing factors of anticipated HIV stigma among HIV-negative/unknown MSM in China: A regression mixture model.

机构信息

School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

Danlan Public Welfare, Beijing, China.

出版信息

Brain Behav. 2024 Apr;14(4):e3472. doi: 10.1002/brb3.3472.

DOI:10.1002/brb3.3472
PMID:38549560
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10979188/
Abstract

BACKGROUND

Anticipated HIV stigma among men who have sex with men's (MSM) has a severe negative effect on their physical and mental health wellbeing and hence requires specific attention. The current study aims to identify the characteristics and the psychosocial influencing factors of anticipated HIV stigma in MSM using regression mixture model (RMM) and to determine the cut-off point of the seven-item Anticipated HIV Stigma Questionnaire (AHSQ) using the receiver operating characteristic (ROC) analysis.

METHODS

A cross-sectional study was conducted among HIV-negative/unknown MSM from Blued online platform in China from December 16th, 2020 to March 1st, 2021, enrolling 1394 participants. Data were collected on demographic characteristics, perceived social support, anticipated HIV stigma, depressive symptoms, and HIV knowledge. Latent profile analysis was performed to identify different profiles of anticipated HIV stigma level. Chi-square test, analysis of variance, and RMM analysis were conducted to explore the influencing factors in different profiles. ROC analyses were carried out to identify the cut-off value of anticipated stigma.

RESULTS

Among the participants, three profiles of anticipated stigma were identified: "low anticipated HIV stigma" (12.0%), "moderate anticipated HIV stigma" (52.1%), and "severe anticipated HIV stigma" (35.9%). RMM analysis showed that higher income and higher levels of knowledge were positively associated with moderate anticipated HIV stigma, whereas full-time job and social support were negatively associated with moderate anticipated HIV stigma; higher income, depressive symptoms, and knowledge were positively associated with severe anticipated HIV stigma, whereas minor ethnicity and social support were negatively associated with severe anticipated HIV stigma. ROC curve of the AHSQ showed that the optimal cut-off value of ≥16 could indicate positive anticipated HIV stigma.

CONCLUSION

The study focuses on the level of anticipated HIV stigma and its psycho-socio influencing factors among HIV-negative/unknown MSM. It provides evidence for implementing relevant psychological interventions to HIV-negative/unknown MSM.

摘要

背景

男男性行为者(MSM)对艾滋病的预期耻辱感对他们的身心健康有严重的负面影响,因此需要特别关注。本研究旨在使用回归混合模型(RMM)识别 MSM 中预期艾滋病耻辱感的特征和心理社会影响因素,并使用受试者工作特征(ROC)分析确定七项预期艾滋病耻辱感问卷(AHSQ)的截断值。

方法

本横断面研究于 2020 年 12 月 16 日至 2021 年 3 月 1 日在中国 Blued 在线平台上招募 HIV 阴性/未知的 MSM,共纳入 1394 名参与者。收集参与者的人口统计学特征、感知社会支持、预期艾滋病耻辱感、抑郁症状和艾滋病知识。采用潜在剖面分析识别预期艾滋病耻辱感水平的不同特征。采用卡方检验、方差分析和 RMM 分析探讨不同特征中的影响因素。ROC 分析确定预期耻辱感的截断值。

结果

在参与者中,确定了三种预期耻辱感特征:“低预期艾滋病耻辱感”(12.0%)、“中度预期艾滋病耻辱感”(52.1%)和“重度预期艾滋病耻辱感”(35.9%)。RMM 分析表明,较高的收入和较高的知识水平与中度预期艾滋病耻辱感呈正相关,而全职工作和社会支持与中度预期艾滋病耻辱感呈负相关;较高的收入、抑郁症状和知识与重度预期艾滋病耻辱感呈正相关,而少数民族和社会支持与重度预期艾滋病耻辱感呈负相关。AHSQ 的 ROC 曲线表明,≥16 的最佳截断值可表明阳性预期艾滋病耻辱感。

结论

本研究关注 HIV 阴性/未知 MSM 中预期艾滋病耻辱感的水平及其心理社会影响因素。为对 HIV 阴性/未知 MSM 实施相关心理干预提供了依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aab/10979188/ccbb59e44400/BRB3-14-e3472-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aab/10979188/a82eac477bcb/BRB3-14-e3472-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aab/10979188/3131b1ce1b65/BRB3-14-e3472-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aab/10979188/ccbb59e44400/BRB3-14-e3472-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aab/10979188/a82eac477bcb/BRB3-14-e3472-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aab/10979188/3131b1ce1b65/BRB3-14-e3472-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aab/10979188/ccbb59e44400/BRB3-14-e3472-g001.jpg

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Effect of the introduction of screening for cancer precursor lesions on anal cancer incidence over time in people living with HIV: a nationwide cohort study.
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