Vuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University Hospital, Zagreb, Croatia.
Bjelovar University of Applied Sciences, Bjelovar, Croatia.
Acta Clin Croat. 2023 Aug;62(2):249-261. doi: 10.20471/acc.2023.62.02.01.
This study compared the self-assessed health-related quality of life (HRQoL) and degree of depression between patients with chronic neuropathic nonodontogenic orofacial pain (NOFP) and healthy controls using the Short Form Survey (SF-36) health status questionnaire and Beck Depression Inventory II (BDI-II). This controlled cross-sectional study included 100 patients and 119 healthy controls. The diagnostic protocol recorded the following: 1) pain intensity using a visual analog scale for the time of examination and during the one-month prior; 2) evidence for neuropathic pain using the Leeds questionnaire for neuropathic signs and symptoms (LANSS); 3) emotional status using the BDI-II; and 4) HRQoL using the SF-36 questionnaire. The mean LANSS score was 17.18 in the patient group and 0.0 in the control group. The mean BDI-II score was 18.31 in the patient group and 5.87 in the control group. The SF-36 scores were shown with Mann-Whitney U testing to have statistically significant differences between the patient and healthy control groups in all categories. Vitality was the only SF-36 category in which the patient group scored higher than the control group. In conclusion, NOFP significantly reduces the self-reported HRQoL. NOFP is also related to the development of depression, but does not affect its severity. There is a significant correlation between depression and low quality of life in patients with NOFP.
本研究采用简明健康状况调查问卷（SF-36）和贝克抑郁量表第二版（BDI-II）比较了慢性非牙源性口腔颌面部神经病理性疼痛（NOFP）患者和健康对照者的自我评估健康相关生活质量（HRQoL）和抑郁程度。这项对照性横断面研究纳入了 100 名患者和 119 名健康对照者。诊断方案记录了以下内容：1）使用视觉模拟量表记录检查时和检查前一个月的疼痛强度；2）使用莱斯特神经病理性疼痛症状和体征问卷（LANSS）记录神经病理性疼痛的证据；3）使用 BDI-II 记录情绪状态；4）使用 SF-36 问卷记录 HRQoL。患者组的平均 LANSS 评分为 17.18，对照组为 0.0。患者组的平均 BDI-II 评分为 18.31，对照组为 5.87。通过曼-惠特尼 U 检验，SF-36 评分在所有类别中均显示患者组与健康对照组之间存在统计学显著差异。活力是患者组评分高于对照组的唯一 SF-36 类别。总之，NOFP 显著降低了自我报告的 HRQoL。NOFP 还与抑郁的发生有关，但不影响其严重程度。NOFP 患者的抑郁与生活质量低下之间存在显著相关性。
