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多发性对称性阴囊脂肪瘤病:诊断与治疗及该疾病的综合概述

Multiple Symmetrical Scrotal Lipomatosis: Diagnosis and Treatment with Comprehensive Summary of the Entity.

作者信息

Szychta Pawel, Witmanowski Henryk

机构信息

From the Dr Szychta Clinic, Gdansk, Poland.

Private Practice, Poznan, Poland.

出版信息

Plast Reconstr Surg Glob Open. 2024 Mar 28;12(3):e5701. doi: 10.1097/GOX.0000000000005701. eCollection 2024 Mar.

DOI:10.1097/GOX.0000000000005701
PMID:38549707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10977562/
Abstract

Multiple symmetrical lipomatosis is a rare diffuse presentation of the progressive accumulation of deposits of nonencapsulated masses of adipose tissue. The characteristic image of this disease is bilateral swelling in the neck, the upper part of upper limb, pelvic rim, back, and thighs. We report a case of unusual localization of benign scrotal symmetrical lipomatosis with ultrasound and histological appearances of the scrotal lipomatous masses, together with treatment. Scrotal lipomatosis should be considered as a rare differential diagnosis of scrotal swelling, and excisional lipectomy should be considered in preference over liposuction. Patients should be offered counseling for infertility.

摘要

多发性对称性脂肪瘤病是一种罕见的脂肪组织非包膜性肿块进行性堆积的弥漫性表现。该病的特征性影像表现为颈部、上肢上部、骨盆边缘、背部和大腿双侧肿胀。我们报告一例阴囊良性对称性脂肪瘤病罕见定位的病例,伴有阴囊脂肪瘤块的超声及组织学表现,以及治疗情况。阴囊脂肪瘤病应被视为阴囊肿胀的一种罕见鉴别诊断,相较于抽脂术,应优先考虑切除性脂肪切除术。应为患者提供关于不育症的咨询。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6574/10977562/d3318c834583/gox-12-e5701-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6574/10977562/84581c4cce88/gox-12-e5701-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6574/10977562/a84950159f42/gox-12-e5701-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6574/10977562/0dad1c11b72f/gox-12-e5701-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6574/10977562/d3318c834583/gox-12-e5701-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6574/10977562/84581c4cce88/gox-12-e5701-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6574/10977562/a84950159f42/gox-12-e5701-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6574/10977562/0dad1c11b72f/gox-12-e5701-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6574/10977562/d3318c834583/gox-12-e5701-g004.jpg

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本文引用的文献

1
Madelung Disease Epidemiology and Clinical Characteristics: a Systemic Review.马德隆病的流行病学和临床特征:系统评价。
Aesthetic Plast Surg. 2021 Jun;45(3):977-986. doi: 10.1007/s00266-020-02083-5. Epub 2021 Jan 25.
2
Transcription Profile in Sporadic Multiple Symmetric Lipomatosis Reveals Differential Expression at the Level of Adipose Tissue-Derived Stem Cells.散发性多发性对称性脂肪瘤病中的转录谱揭示了脂肪组织来源干细胞水平的差异表达。
Plast Reconstr Surg. 2016 Apr;137(4):1181-1190. doi: 10.1097/PRS.0000000000002013.
3
Scrotal Lipomatosis Mimicking Varicocele: A Case Report and Review of the Literature.
酷似精索静脉曲张的阴囊脂肪过多症:一例报告并文献复习
Case Rep Urol. 2015;2015:695314. doi: 10.1155/2015/695314. Epub 2015 Nov 17.
4
Madelung disease: a rare case associated with gynaecomastia and scrotal involvement.马德隆病:一例与男性乳房发育及阴囊受累相关的罕见病例。
J Plast Surg Hand Surg. 2013 Oct;47(5):415-8. doi: 10.3109/2000656X.2012.729627. Epub 2013 May 22.
5
Multiple benign symmetric lipomatosis--a differential diagnosis of obesity: is there a rationale for fibrate treatment?多发性对称性脂肪瘤病——肥胖的鉴别诊断:贝特类药物治疗是否有理论依据?
Obes Surg. 2008 Feb;18(2):240-2. doi: 10.1007/s11695-007-9247-3. Epub 2008 Jan 4.
6
Benign symmetric lipomatosis of the tongue in Madelung's disease.马德隆病中的舌部良性对称性脂肪瘤病
J Craniomaxillofac Surg. 2006 Dec;34(8):489-93. doi: 10.1016/j.jcms.2006.06.003. Epub 2006 Dec 8.
7
Scrotal involvement in Madelung disease: clinical, ultrasound and MR findings.马德隆病累及阴囊:临床、超声及磁共振成像表现
Abdom Imaging. 2006 Jul-Aug;31(4):503-5. doi: 10.1007/s00261-005-0401-x.
8
Madelung syndrome (benign lipomatosis): clinical course and treatment.马德隆综合征(良性脂肪增多症):临床病程与治疗
Scand J Plast Reconstr Surg Hand Surg. 2004;38(4):240-3. doi: 10.1080/02844310410025295.
9
Combined surgical lipectomy and liposuction in the treatment of benign symmetrical lipomatosis of the head and neck.联合手术脂肪切除术和抽脂术治疗头颈部良性对称性脂肪瘤病
Scand J Plast Reconstr Surg Hand Surg. 2003;37(2):90-6. doi: 10.1080/02844310310005612.
10
Scrotal lipomatosis.阴囊脂肪过多症
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