Suppr超能文献

以巨大腹腔内肿物为表现的小网膜胃肠道外间质瘤:1例报告及文献复习

Extra-gastrointestinal stromal tumour of the lesser omentum presenting as a massive intra-abdominal swelling: A case report and literature review.

作者信息

Ashindoitiang John Adi, Nwagbara Victor Ikechukwu Canice, Ugbem Theophilus Ipeh, Enya Nkami Joseph, Aniebo Ikechimka Ogbugbanduchi, Ekong Joseph Christopher, Obinna Sidney Esotu, Asuquo Maurice Efana

机构信息

Department of Surgery, University of Calabar/University of Calabar Teaching Hospital, Calabar.

Department of Pathology, University of Calabar/University of Calabar Teaching Hospital, Calabar.

出版信息

Rare Tumors. 2024 Mar 27;16:20363613241242572. doi: 10.1177/20363613241242572. eCollection 2024.

Abstract

Extra gastrointestinal stromal tumour(EGIST) is rare and is regarded as gastrointestinal stromal tumour(GIST) that originates outside of the gastrointestinal tract. They originate from other intraabdominal tissues such as the omentum, mesentery and peritoneum. The cell of origin is the interstitial cell of Cajal(ICC), a pacemaker cell that controls gastrointestinal peristalsis and the tumor is characterized by the expression of KIT(CD117) a transmembrane tyrosine kinase receptor. Here, a 49-year-old female who presented with a 6 month history of abdominal pain, progressive abdominal swelling and the presence of an upper abdominal mass. She had surgical resection and adjuvant imatinib for the intraabdominal mass diagnosed on histology and immunohistochemistry as EGIST of the lesser omentum. Serial CT 14 months after surgery revealed no evidence of recurrence or metastasis. Clinicians should consider EGIST in the differential diagnosis of abdominal masses.

摘要

胃肠道外间质瘤(EGIST)较为罕见,被视为起源于胃肠道外的胃肠道间质瘤(GIST)。它们起源于其他腹腔内组织,如大网膜、肠系膜和腹膜。其起源细胞是 Cajal 间质细胞(ICC),一种控制胃肠蠕动的起搏细胞,该肿瘤的特征是表达 KIT(CD117),一种跨膜酪氨酸激酶受体。在此,一名49岁女性,有6个月的腹痛病史、进行性腹部肿胀,且上腹部有肿块。她接受了手术切除,并对经组织学和免疫组织化学诊断为小网膜EGIST的腹腔肿块进行了辅助伊马替尼治疗。术后14个月的系列CT检查未发现复发或转移迹象。临床医生在腹部肿块的鉴别诊断中应考虑EGIST。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ded/10976504/5c714aba96bd/10.1177_20363613241242572-fig1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验