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前列腺原发性滤泡性淋巴瘤与5级前列腺腺癌并存，并在多参数磁共振成像（mpMRI）上表现为PI-RADS 4类病变。

Primary follicular lymphoma of the prostate co-existing with grade group 5 prostatic adenocarcinoma and presenting as a PI-RADS lesion 4 on mpMRI.

作者信息

Bal Shubhneet, Odujoko Oluwole, Fiedler Jacob, Sieber Steven C, Beck Edward, Gupta Gunjan

机构信息

Pathology & Laboratory Medicine Department, Danbury Hospital, Danbury, 06810, CT, United States.

New York Medical College, Valhalla, 10595, NY, United States.

出版信息

Urol Case Rep. 2024 Mar 12;54:102708. doi: 10.1016/j.eucr.2024.102708. eCollection 2024 May.

DOI:10.1016/j.eucr.2024.102708
PMID:38550656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10973778/
Abstract

Primary prostatic lymphoma is an exceedingly rare entity comprising less than 0.09% of all prostatic cancers with follicular lymphoma making up only 12% as a subset. To our knowledge, primary follicular lymphoma co-existing with high grade prostatic adenocarcinoma presenting as a PI-RADS lesion 4 on mpMRI has not been previously described. We report the case of a 73-year-old male who presented with mildly elevated PSA and lower urinary tract symptoms. Prostate needle biopsy revealed low grade follicular lymphoma juxtaposed with high grade prostatic adenocarcinoma. The patient has been treated with radiation therapy for adenocarcinoma and is under observation for lymphoma progression.

摘要

原发性前列腺淋巴瘤是一种极为罕见的疾病，在所有前列腺癌中占比不到0.09%，其中滤泡性淋巴瘤仅占12%。据我们所知，之前尚未有原发性滤泡性淋巴瘤与高级别前列腺腺癌并存且在多参数磁共振成像（mpMRI）上表现为前列腺影像报告和数据系统（PI-RADS）4类病变的报道。我们报告了一例73岁男性患者，其前列腺特异性抗原（PSA）轻度升高并伴有下尿路症状。前列腺穿刺活检显示低级别滤泡性淋巴瘤与高级别前列腺腺癌并存。该患者已接受针对腺癌的放射治疗，目前正在观察淋巴瘤的进展情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/018a/10973778/a1733ddad5eb/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/018a/10973778/51cc2e470f62/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/018a/10973778/d64ede78c5b2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/018a/10973778/a1733ddad5eb/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/018a/10973778/51cc2e470f62/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/018a/10973778/d64ede78c5b2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/018a/10973778/a1733ddad5eb/gr3.jpg

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本文引用的文献

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前列腺原发性淋巴瘤：基于阿霉素的联合化疗疗效良好。
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