Bauman Moscow State Technical University, Moscow, Russia.
Peoples' Friendship University of Russia (RUDN University), Moscow, Russia.
Colloids Surf B Biointerfaces. 2024 May;237:113861. doi: 10.1016/j.colsurfb.2024.113861. Epub 2024 Mar 24.
Copper and copper oxide nanoparticles (CuNPs) have unique physicochemical properties that make them highly promising for biomedical applications. This review discusses the application of CuNPs in biomedicine, including diagnosis, therapy, and theranostics. Recent synthesis methods, with an emphasis on green approaches, are described, and the latest techniques for nanoparticle characterization are critically analyzed. CuNPs, including CuO, CuO, and Cu, have significant potential as anti-cancer agents, drug delivery systems, and photodynamic therapy enhancers, among other applications. While challenges such as ensuring biocompatibility and stability must be addressed, the state-of-the-art research reviewed here provides strong evidence for the efficacy and versatility of CuNPs. These multifunctional properties have been extensively researched and documented, showcasing the immense potential of CuNPs in biomedicine. Overall, the evidence suggests that CuNPs are a promising avenue for future research and development in biomedicine. We strongly support further progress in the development of synthesis and application strategies to enhance the effectiveness and safety of CuNPs for clinical purposes.
铜和氧化铜纳米粒子(CuNPs)具有独特的物理化学性质,使其在生物医学应用中极具应用前景。本综述讨论了 CuNPs 在生物医学中的应用,包括诊断、治疗和治疗学。描述了最近的合成方法,重点是绿色方法,并对纳米粒子表征的最新技术进行了批判性分析。CuNPs,包括 CuO、CuO 和 Cu,具有作为抗癌剂、药物传递系统和光动力治疗增强剂等应用的巨大潜力。虽然必须解决确保生物相容性和稳定性等挑战,但这里综述的最新研究为 CuNPs 的功效和多功能性提供了有力证据。这些多功能特性已经得到了广泛的研究和记录,展示了 CuNPs 在生物医学中的巨大潜力。总的来说,有证据表明,CuNPs 是生物医学未来研究和发展的一个有前途的途径。我们强烈支持进一步推进合成和应用策略的发展,以提高 CuNPs 用于临床目的的有效性和安全性。