饮食中晚期糖基化终产物、身体成分和人体测量指标：超重女性的横断面分析。

Dietary advanced glycation end products, body composition, and anthropometric measures: A cross-sectional analysis in women with excess body weight.

机构信息

Department of Nutrition and Health, Universidade Federal de Viçosa, Campus Universitário, s/nº, Av. Peter Henry Rolfs, Centro, 35570-900, Viçosa, MG, Brazil.

出版信息

Nutr Metab Cardiovasc Dis. 2024 Jul;34(7):1721-1730. doi: 10.1016/j.numecd.2024.03.011. Epub 2024 Mar 12.

DOI:10.1016/j.numecd.2024.03.011

PMID:38555239

Abstract

BACKGROUND AND AIMS

To assess the association between dietary advanced glycation end products (dAGEs) versus body composition and anthropometric variables.

METHODS AND RESULTS

Body composition (dual-energy X-ray absorptiometry), anthropometry, and habitual food intake were cross-sectionally evaluated in women with excess body weight and body fat. Mean dAGEs content was estimated using a database containing the N-(carboxymethyl)lysine (CML) content of 549 foods, which was adjusted by mean energy intake, and categorized into low, medium, and high dAGEs, by the 10th and 50th percentiles of the sample. Associations were tested by linear regression adjusted for age, education, marital status, and physical activity level. Eighty participants had mean ± standard deviation dAGEs 7.85 ± 2.65 AGEs kU/kcal. Compared with high dAGEs, women with low dAGEs ingested more carbohydrate (62% vs. 50% of calories, p < 0.001) and fiber (≈25 g vs. ≈18 g, p = 0.027) and less protein (13% vs. 17% of calories, p = 0.006) and fat (26% vs. 33% of calories, p = 0.011). Women with low dAGEs had waist/hip ratio 0.05 higher than those with high dAGEs (R = 0.256, p = 0.005). Low dAGEs relative to medium (p = 0.009) and high (p = 0.002) dAGEs was associated with a ≈5% gynoid fat reduction (R = 0.164).

CONCLUSION

Low dAGEs was associated with a higher waist/hip ratio and lower percentage of gynoid fat in women with excess body weight and excess body fat.

REGISTRATION NUMBER

RBR-7z358j.

摘要

背景和目的

评估饮食晚期糖基化终产物（dAGEs）与身体成分和人体测量变量之间的关联。

方法和结果

在超重和体脂过多的女性中，采用双能 X 射线吸收法测定身体成分、人体测量和习惯性食物摄入量。使用包含 549 种食物中 N-（羧甲基）赖氨酸（CML）含量的数据库来估计平均 dAGEs 含量，该数据库通过平均能量摄入进行了调整，并根据样本的第 10 和第 50 百分位数分为低、中、高 dAGEs。通过线性回归调整年龄、教育程度、婚姻状况和体力活动水平来测试相关性。80 名参与者的平均 dAGEs 为 7.85±2.65 AGEs kU/kcal。与高 dAGEs 组相比，低 dAGEs 组摄入更多的碳水化合物（62% vs. 50%的卡路里，p<0.001）和纤维（≈25 g vs. ≈18 g，p=0.027），更少的蛋白质（13% vs. 17%的卡路里，p=0.006）和脂肪（26% vs. 33%的卡路里，p=0.011）。低 dAGEs 组的腰围/臀围比比高 dAGEs 组高 0.05（R=0.256，p=0.005）。与中（p=0.009）和高（p=0.002）dAGEs 相比，低 dAGEs 与 gynoid 脂肪减少约 5%相关（R=0.164）。