Kowalczyk J R, Sandberg A A
Cancer Genet Cytogenet. 1985 Feb 15;15(3-4):303-8. doi: 10.1016/0165-4608(85)90174-8.
Complete remission rates, remission duration, and survival were established in children with acute lymphoblastic leukemia (ALL) with chromosome #1 anomalies, and the results were compared with those in patients with normal karyotypes or other chromosomal changes. Even though the complete remission rate did not differ significantly among the three groups, remission duration and survival were significantly longer in children ALL and chromosome #1 anomalies as compared with those in the other two groups.
在患有1号染色体异常的急性淋巴细胞白血病(ALL)儿童中确定了完全缓解率、缓解持续时间和生存率,并将结果与核型正常或有其他染色体变化的患者进行了比较。尽管三组之间的完全缓解率没有显著差异,但与其他两组相比,患有1号染色体异常的儿童ALL的缓解持续时间和生存率明显更长。