6号染色体长臂与人类恶性黑色素瘤的关系。

Chromosome 6q involvement in human malignant melanoma.

作者信息

Trent J M, Rosenfeld S B, Meyskens F L

出版信息

Cancer Genet Cytogenet. 1983 Jun;9(2):177-80. doi: 10.1016/0165-4608(83)90039-0.

Abstract

Chromosome banding analysis was performed on five cases of human malignant melanoma. Results demonstrated a variety of chromosome alterations, including deletion or translocation of chromosome 6q, in four of five cases. A comparison of our results with previously published studies suggests that chromosome 6q may represent a specific site of chromosome aberration in malignant melanoma.

摘要

对五例人类恶性黑色素瘤进行了染色体显带分析。结果显示了多种染色体改变，包括五例中的四例出现6号染色体长臂的缺失或易位。将我们的结果与先前发表的研究进行比较表明，6号染色体长臂可能代表恶性黑色素瘤中染色体畸变的一个特定部位。