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基于证据的子宫中隔诊断与治疗:指南。

Evidence-based diagnosis and treatment for uterine septum: a guideline.

机构信息

The American Society for Reproductive Medicine, Washington, D.C.

出版信息

Fertil Steril. 2024 Aug;122(2):251-265. doi: 10.1016/j.fertnstert.2024.02.033. Epub 2024 Apr 1.

DOI:10.1016/j.fertnstert.2024.02.033
PMID:38556964
Abstract

OBJECTIVE

To provide evidence-based recommendations regarding the diagnosis and effectiveness of surgical treatment of a uterine septum.

METHODS

This guideline provides evidence-based recommendations regarding the diagnosis and effectiveness of surgical treatment of a uterine septum. This replaces the last version of the same name (Fertil Steril. 2016 Sep 1;106(3):530-40).

MAIN OUTCOME MEASURE(S): Outcomes of interest included the impact of a septum on underlying fertility, live birth, clinical pregnancy, and obstetrical outcomes.

RESULT(S): The literature search identified relevant studies to inform the evidence for this guideline.

CONCLUSION(S): The treatment of uterine septa and subsequent outcomes associated with infertility, recurrent pregnancy loss, and adverse obstetrical outcomes are summarized. Resection of a septum has been shown to improve outcomes in patients with recurrent pregnancy loss and to decrease the likelihood of malpresentation. In the setting of infertility, it is recommended to use a shared decision-making model after appropriate counseling to determine whether or not to proceed with septum resection.

摘要

目的

提供有关子宫中隔诊断和手术治疗效果的循证建议。

方法

本指南提供了有关子宫中隔诊断和手术治疗效果的循证建议。本指南取代了同名指南的上一版本(Fertil Steril. 2016 Sep 1;106(3):530-40)。

主要观察指标

感兴趣的结局包括中隔对潜在生育力、活产、临床妊娠和产科结局的影响。

结果

文献检索确定了相关研究,为指南提供了证据。

结论

总结了子宫中隔的治疗及其与不孕、复发性妊娠丢失和不良产科结局相关的后续结局。切除中隔已被证明可以改善复发性妊娠丢失患者的结局,并降低胎位不正的可能性。在不孕的情况下,建议在适当咨询后使用共同决策模型,以确定是否进行中隔切除术。

相似文献

1
Evidence-based diagnosis and treatment for uterine septum: a guideline.基于证据的子宫中隔诊断与治疗:指南。
Fertil Steril. 2024 Aug;122(2):251-265. doi: 10.1016/j.fertnstert.2024.02.033. Epub 2024 Apr 1.
2
Reproductive outcomes after uterine septum resection in patients with recurrent miscarriage or infertility: a retrospective study in Chinese women.反复性流产或不孕患者行子宫中隔切除术的生殖结局:一项中国女性的回顾性研究。
Arch Gynecol Obstet. 2023 Feb;307(2):609-617. doi: 10.1007/s00404-022-06794-9. Epub 2022 Oct 11.
3
Uterine septum: a guideline.子宫中隔:指南。
Fertil Steril. 2016 Sep 1;106(3):530-40. doi: 10.1016/j.fertnstert.2016.05.014. Epub 2016 May 25.
4
Reproductive outcomes of natural pregnancy after hysteroscopic septum resection in patients with a septate uterus: a systematic review and meta-analysis.有子宫纵隔的患者行宫腔镜下纵隔切除术自然妊娠的结局:系统评价和荟萃分析。
Am J Obstet Gynecol MFM. 2023 Jan;5(1):100762. doi: 10.1016/j.ajogmf.2022.100762. Epub 2022 Oct 8.
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Effect of Hysteroscopic Metroplasty on Reproductive Outcomes in Women with Septate Uterus: Systematic Review and Meta-Analysis.宫腔镜子宫中隔切除术对纵隔子宫患者生殖结局的影响:系统评价和荟萃分析。
J Minim Invasive Gynecol. 2022 Apr;29(4):465-475. doi: 10.1016/j.jmig.2021.10.001. Epub 2021 Oct 11.
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Uterine Septum and Other Müllerian Anomalies in a Recurrent Pregnancy Loss Population: Impact on Reproductive Outcomes.复发性流产人群中的子宫纵隔及其他苗勒管异常:对生殖结局的影响。
J Minim Invasive Gynecol. 2023 Dec;30(12):961-969. doi: 10.1016/j.jmig.2023.07.012. Epub 2023 Jul 26.
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Hysteroscopic septum resection in patients with recurrent abortions or infertility.复发性流产或不孕症患者的宫腔镜下纵隔切除术
Hum Reprod. 1998 May;13(5):1188-93. doi: 10.1093/humrep/13.5.1188.
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Septum resection in women with a septate uterus: a cohort study.纵隔子宫女性的纵隔切除术:一项队列研究。
Hum Reprod. 2020 Jul 1;35(7):1578-1588. doi: 10.1093/humrep/dez284.
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Effects of hysteroscopic septum incision versus expectant management on IVF outcomes in women with complete septate uterus: a retrospective study.宫腔镜下子宫纵隔切开术与期待治疗对完全性子宫纵隔患者 IVF 结局的影响:一项回顾性研究。
BMC Womens Health. 2024 Mar 30;24(1):202. doi: 10.1186/s12905-024-03022-1.
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The randomised uterine septum transsection trial (TRUST): design and protocol.随机子宫纵隔横断试验(TRUST):设计与方案
BMC Womens Health. 2018 Oct 5;18(1):163. doi: 10.1186/s12905-018-0637-6.

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Ther Adv Reprod Health. 2025 Jun 21;19:26334941251345844. doi: 10.1177/26334941251345844. eCollection 2025 Jan-Dec.
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Complete uterine septum, cervical septum and longitudinal vaginal septum: a challenging differential diagnosis with double cervix.完全性子宫纵隔、宫颈纵隔及阴道纵膈:与双宫颈的鉴别诊断难题
Facts Views Vis Obgyn. 2025 Mar 28;17(1):84-89. doi: 10.52054/FVVO.2024.13721.
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Effect of hysteroscopic septum resection on IVF/ICSI outcomes in women with septate uterus: a propensity-score retrospective matching study.
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Reprod Biol Endocrinol. 2025 Apr 8;23(1):53. doi: 10.1186/s12958-025-01378-z.
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Safety and effectiveness of office hysteroscopic metroplasty with and without uterine stent placement in infertile population: a 10-year retrospective study.在不孕人群中宫腔镜下子宫成形术联合或不联合放置子宫支架的安全性和有效性:一项10年回顾性研究
Ther Adv Reprod Health. 2025 Mar 21;19:26334941251324951. doi: 10.1177/26334941251324951. eCollection 2025 Jan-Dec.