Zhang Ting, Jiang Mi-Zu
Department of Gastroenterology and Pediatric Endoscopy Center, Children's Hospital, Zhejiang University School of Medicine/National Clinical Research Center for Child Health/National Children's Regional Medical Center, Hangzhou 310052, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2024 Mar 15;26(3):308-314. doi: 10.7499/j.issn.1008-8830.2310014.
Hematopoietic stem cell transplantation (HSCT) is a therapeutic option for various potentially life-threatening malignant and non-malignant diseases in children, such as malignancies, immunodeficiency syndromes, severe aplastic anemia, and inherited metabolic disorders. During transplantation, many factors can affect the nutritional status of the children, including radiotherapy, chemotherapy, gastrointestinal disorders, graft-versus-host disease, and medications. Malnutrition has been associated with decreased overall survival and increased complications in children undergoing HSCT, making nutritional support a crucial component of their management. However, currently, there is a lack of guidelines or consensus on nutritional support for children undergoing HSCT in China. Therefore, this review summarizes the progress in nutritional support for children undergoing HSCT, aiming to provide clinical guidance.
造血干细胞移植（HSCT）是治疗儿童各种潜在危及生命的恶性和非恶性疾病的一种选择，如恶性肿瘤、免疫缺陷综合征、重型再生障碍性贫血和遗传性代谢紊乱。在移植过程中，许多因素会影响儿童的营养状况，包括放疗、化疗、胃肠道疾病、移植物抗宿主病和药物。营养不良与接受HSCT的儿童总体生存率降低和并发症增加有关，这使得营养支持成为其治疗的关键组成部分。然而，目前在中国，对于接受HSCT的儿童的营养支持缺乏指南或共识。因此，本综述总结了接受HSCT的儿童营养支持的进展，旨在提供临床指导。
