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Efficacy and safety of bilastine vs. levocetirizine for the treatment of chronic idiopathic urticaria: A multicenter, double-blind, double-dummy, phase III, non-inferiority, randomized clinical trial.

作者信息

Chen Xue, Han Xiuping, Cheng Bo, Li Hui, Liu Lingling, Geng Songmei, Li Linfeng, Li Jie, Guo Qing, Zhang Guoyi, Fang Hong, Zhang Jianzhong

机构信息

Department of Dermatology, Peking University People's Hospital, Beijing 100044, China.

Department of Dermatology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110055, China.

出版信息

Chin Med J (Engl). 2024 Jun 20;137(12):1480-1482. doi: 10.1097/CM9.0000000000003071. Epub 2024 Apr 1.

DOI:10.1097/CM9.0000000000003071
PMID:38557589
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11188862/
Abstract
摘要

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Comparison of the efficacy and safety of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic idiopathic urticaria: a multi-centre, double-blind, randomized, placebo-controlled study.比较比利司特 20 毫克与左西替利嗪 5 毫克治疗慢性特发性荨麻疹的疗效和安全性：一项多中心、双盲、随机、安慰剂对照研究。
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BMC Pharmacol Toxicol. 2024 Dec 18;25(1):95. doi: 10.1186/s40360-024-00822-x.
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本文引用的文献

1
Effect of Bilastine on Chronic Urticaria: A Systematic Review and Meta-Analysis.比拉斯汀治疗慢性荨麻疹的疗效：系统评价和荟萃分析。
Int Arch Allergy Immunol. 2023;184(2):176-185. doi: 10.1159/000527181. Epub 2022 Nov 11.
2
Epidemiology of urticaria in China: a population-based study.中国荨麻疹的流行病学：一项基于人群的研究。
Chin Med J (Engl). 2022 Jun 5;135(11):1369-1375. doi: 10.1097/CM9.0000000000002172.
3
Effectiveness, safety, and tolerability of bilastine 20 mg vs levocetirizine 5 mg for the treatment of chronic spontaneous urticaria: A double-blind, parallel group, randomized controlled trial.
20毫克比拉斯汀与5毫克左西替利嗪治疗慢性自发性荨麻疹的有效性、安全性及耐受性：一项双盲、平行组、随机对照试验
Dermatol Ther. 2020 Nov;33(6):e13946. doi: 10.1111/dth.13946. Epub 2020 Jul 27.
4
Antihistamines for Allergic Rhinitis Treatment from the Viewpoint of Nonsedative Properties.抗组胺药治疗变应性鼻炎的非镇静作用观点。
Int J Mol Sci. 2019 Jan 8;20(1):213. doi: 10.3390/ijms20010213.
5
Treatment of allergic rhinitis and urticaria: a review of the newest antihistamine drug bilastine.过敏性鼻炎和荨麻疹的治疗：新型抗组胺药物比拉斯汀综述
Ther Clin Risk Manag. 2016 Apr 13;12:585-97. doi: 10.2147/TCRM.S105189. eCollection 2016.