R Sangavi, Pandiyan Indumathy
Department of Oral Medicine, Radiology, and Special Care Dentistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, IND.
Department of Public Health Dentistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Cureus. 2024 Feb 29;16(2):e55213. doi: 10.7759/cureus.55213. eCollection 2024 Feb.
Oral mucositis (OM) is a major and common adverse reaction to cancer treatment, occurring in all patients who undergo radiation therapy or chemotherapy that includes the mucosal areas of the oral and oropharyngeal region. The pathophysiology of OM remains incompletely understood, and there are many unanswered questions about the risk factors for developing OM. Multidisciplinary clinicians and researchers must collaborate to better understand and expand treatment strategies for OM and other inflammatory conditions in oncology. This will lead to the development of more effective treatments and reduce the burden of OM in cancer patients. This article comprehensively reviews the risk factors and patient factors associated with OM, its pathogenesis, clinical presentation, grading, and management.
口腔黏膜炎（OM）是癌症治疗中一种主要且常见的不良反应，发生于所有接受包括口腔和口咽区域黏膜部位的放射治疗或化疗的患者。OM的病理生理学仍未完全明确，关于发生OM的风险因素仍有许多未解答的问题。多学科临床医生和研究人员必须合作，以更好地理解并扩展针对OM及肿瘤学中其他炎症性疾病的治疗策略。这将促成更有效的治疗方法的开发，并减轻癌症患者的OM负担。本文全面综述了与OM相关的风险因素和患者因素、其发病机制、临床表现、分级及管理。
