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采用三维打印技术制备生物制药。

Formulating biopharmaceuticals using three-dimensional printing.

机构信息

School of Pharmacy, University of Waterloo, Kitchener, ON, Canada.

Waterloo Institute for Nanotechnology, Waterloo, ON, Canada.

出版信息

J Pharm Pharm Sci. 2024 Mar 15;27:12797. doi: 10.3389/jpps.2024.12797. eCollection 2024.

Abstract

Additive manufacturing, commonly referred to as three-dimensional (3D) printing, has the potential to initiate a paradigm shift in the field of medicine and drug delivery. Ever since the advent of the first-ever United States Food and Drug Administration (US FDA)-approved 3D printed tablet, there has been an increased interest in the application of this technology in drug delivery and biomedical applications. 3D printing brings us one step closer to personalized medicine, hence rendering the "one size fits all" concept in drug dosing obsolete. In this review article, we focus on the recent developments in the field of modified drug delivery systems in which various types of additive manufacturing technologies are applied.

摘要

增材制造,通常被称为三维(3D)打印,有可能引发医学和药物输送领域的范式转变。自从第一个获得美国食品和药物管理局(US FDA)批准的 3D 打印片剂问世以来,人们对该技术在药物输送和生物医学应用中的应用越来越感兴趣。3D 打印使我们更接近个性化医疗,从而使药物剂量的“一刀切”概念过时。在这篇综述文章中,我们专注于改性药物输送系统领域的最新发展,其中应用了各种类型的增材制造技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0f/10979422/8de7f9ca6620/jpps-27-12797-g001.jpg

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