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儿童尺骨干单灶性结核性骨髓炎:一例报告

Unifocal Tubercular Osteomyelitis of Ulna Diaphysis in a Child: A Case Report.

作者信息

Ulhaque Furquan, Rahman Syed Hifzur, Rai Abhishek Kumar, Hadole Bhushan Sunil, Meghashyama K S, Kumar K G Geekesh

机构信息

Department of Orthopaedics, Seth GS Medical College and KEM hospital, Mumbai, Maharashtra, India.

Department of Orthopaedics, Pandit Madan Mohan Malviya Shatabdi Centenary Hospital, Mumbai, Maharashtra, India.

出版信息

J Orthop Case Rep. 2024 Mar;14(3):119-123. doi: 10.13107/jocr.2024.v14.i03.4312.

Abstract

INTRODUCTION

Osteoarticular tuberculosis (OATB) contributes to around 10% of extrapulmonary tuberculosis of which the spine is the most common site. Isolated involvement of ulna diaphysis is extremely rare. We present a case of unifocal tuberculous osteomyelitis of ulna diaphysis in a 3 -year-old male child and highlight its resemblance with musculoskeletal tumors and stress the importance of GeneXpert mycobacterium tuberculosis (MTB)/resistance to rifampicin (RIF) in the diagnosis of OATB.

CASE REPORT

A mother of a 2-year-old male child incidentally noticed that her son complained of left forearm pain. She was not sure of any fall or trauma to the forearm. No history of fever or other constitutional symptoms was present. Clinical examination was uneventful except for local tenderness in over the dorsomedial aspect of the left mid forearm. A plain radiograph revealed an oval solitary lytic lesion over distal one-third ulna diaphysis. A needle biopsy was done after clinical, hematological, and radiological evaluation, and finally, GeneXpert detected tuberculosis without RIF. No further tests were required and the child was started on antitubercular therapy (ATT) which resulted in complete healing without any symptoms.

CONCLUSION

The authors conclude that it is therefore essential to consider tuberculosis in the differential diagnosis while evaluating a lytic bone lesion. Where possible, all patients should have a biopsy of the lesion and provide a specimen for GeneXpert MTB/RIF to confirm the diagnosis and drug susceptibility testing.

摘要

引言

骨关节结核(OATB)约占肺外结核的10%,其中脊柱是最常见的发病部位。尺骨干单独受累极为罕见。我们报告一例3岁男童尺骨干单灶性结核性骨髓炎病例,强调其与肌肉骨骼肿瘤的相似之处,并强调Xpert MTB/RIF(结核分枝杆菌/利福平耐药性检测)在骨关节结核诊断中的重要性。

病例报告

一名2岁男童的母亲偶然注意到儿子诉说左前臂疼痛。她不确定前臂是否有跌倒或外伤史。无发热或其他全身症状史。临床检查无异常,仅左前臂中部背内侧局部压痛。X线平片显示尺骨远端三分之一骨干处有一个椭圆形孤立性溶骨性病变。在进行临床、血液学和放射学评估后进行了针吸活检,最终Xpert MTB/RIF检测发现结核但对利福平敏感。无需进一步检查,患儿开始接受抗结核治疗(ATT),最终完全康复且无任何症状。

结论

作者得出结论,因此在评估溶骨性骨病变时,在鉴别诊断中考虑结核至关重要。在可能的情况下,所有患者均应进行病变活检,并提供标本进行Xpert MTB/RIF检测,以确诊并进行药敏试验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/876a/10976547/e577f11304fb/JOCR-14-119-g001.jpg

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