Zerriouh Meriem, De Clifford-Faugère Gwenaelle, Nguena Nguefack Hermine Lore, Pagé M Gabrielle, Guénette Line, Blais Lucie, Lacasse Anaïs
Département des Sciences de la Santé, Université du Québec en Abitibi-Témiscamingue (UQAT), Rouyn-Noranda, QC, Canada.
Centre de Recherche, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, QC, Canada.
Front Pain Res (Lausanne). 2024 Mar 15;5:1306479. doi: 10.3389/fpain.2024.1306479. eCollection 2024.
Randomized clinical trials are used to evaluate the efficacy of various pain treatments individually, while a limited number of observational studies have portrayed the overall relief experienced by persons living with chronic pain. This study aimed to describe pain relief in real-world clinical settings and to identify associated factors.
This exploratory web-based cross-sectional study used data from 1,419 persons recruited in the community. Overall pain relief brought by treatments used by participants was assessed using a 0%-100% scale (10-unit increments).
A total of 18.2% of participants reported minimal pain relief (0%-20%), 60.0% moderate to substantial pain relief (30%-60%), and 21.8% extensive pain relief (70%-100%). Multivariable multinomial regression analysis revealed factors significantly associated with greater pain relief, including reporting a stressful event as circumstances surrounding the onset of pain, living with pain for ≥10 years, milder pain intensity, less catastrophic thinking, use of prescribed pain medications, use of nonpharmacological pain treatments, access to a trusted healthcare professional, higher general health scores, and polypharmacy. Factors associated with lower pain relief included surgery as circumstances surrounding pain onset, use of over-the-counter pain medications, and severe psychological distress.
In this community sample of persons living with chronic pain, 8 out of 10 persons reported experiencing at least moderate relief with their treatment. The analysis has enabled us to explore potential modifiable factors as opportunities for improving the well-being of persons living with chronic pain.
随机临床试验用于单独评估各种疼痛治疗方法的疗效，而仅有少数观察性研究描述了慢性疼痛患者所体验到的总体疼痛缓解情况。本研究旨在描述现实临床环境中的疼痛缓解情况并确定相关因素。
这项基于网络的探索性横断面研究使用了从社区招募的1419人的数据。使用0%-100%的量表（以10个单位递增）评估参与者所使用治疗方法带来的总体疼痛缓解情况。
共有18.2%的参与者报告疼痛缓解程度极小（0%-20%），60.0%报告中度至显著疼痛缓解（30%-60%），21.8%报告广泛疼痛缓解（70%-100%）。多变量多项回归分析揭示了与更大程度疼痛缓解显著相关的因素，包括将压力事件报告为疼痛发作时的情况、疼痛持续≥10年、疼痛强度较轻、灾难化思维较少、使用处方止痛药物、使用非药物性疼痛治疗方法、能接触到可信赖的医疗保健专业人员、一般健康评分较高以及使用多种药物。与较低疼痛缓解相关的因素包括手术作为疼痛发作时的情况、使用非处方止痛药物以及严重的心理困扰。
在这个慢性疼痛患者的社区样本中，十分之八的人报告其治疗至少带来了中度缓解。该分析使我们能够探索潜在的可改变因素，将其作为改善慢性疼痛患者幸福感的机会。
