侵袭性肺曲霉病患者连续支气管肺泡灌洗液半乳甘露聚糖水平与治疗反应
Serial Bronchoalveolar Lavage Fluid Galactomannan and Treatment Response in Invasive Pulmonary Aspergillosis.
作者信息
Friedman Daniel Z P, Theel Elitza S, Walker Randall C, Vikram Holenarasipur R, Razonable Raymund R, Vergidis Paschalis
机构信息
Section of Infectious Disease, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Section of Infectious Diseases and Public Health, University of Chicago, Chicago, Illinois, USA.
出版信息
Open Forum Infect Dis. 2024 Mar 1;11(4):ofae114. doi: 10.1093/ofid/ofae114. eCollection 2024 Apr.
We studied patients diagnosed with aspergillosis based on positive bronchoalveolar lavage (BAL) galactomannan (GM) who had follow-up BAL sampling within 180 days. GM trend and clinical outcome were concordant in only 60% (30/50). While useful for the initial diagnosis, BAL GM trending does not always correlate with treatment response.
我们研究了那些根据支气管肺泡灌洗（BAL）半乳甘露聚糖（GM）检测呈阳性而被诊断为曲霉病且在180天内进行了随访BAL采样的患者。GM趋势与临床结果仅在60%（30/50）的患者中一致。虽然BAL GM检测趋势对初始诊断有用，但它并不总是与治疗反应相关。
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