Aderounmu Adewale A, Olasehinde Olalekan, Wuraola Funmilola O, Adisa Adewale O, Lawal Oladejo O
Department of Surgery, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
Department of Surgery, Obafemi Awolowo University, Ile-Ife, Nigeria.
J West Afr Coll Surg. 2024 Apr-Jun;14(2):154-158. doi: 10.4103/jwas.jwas_25_23. Epub 2024 Feb 22.
Interest in surgical site infections (SSI) has been sustained over the years because its occurrence may be ruinous to the overall success of surgical operations. The use of antimicrobial suture has been associated with a reduction in SSI, but its role in open appendectomy has not been evaluated.
This study compared the effect of fascia closure with triclosan-coated polydioxanone (PDS) with plain PDS on SSI in appendectomy wounds.
Ninety-three consecutive patients who had open appendectomy for uncomplicated acute appendicitis were randomised to either have fascia closure with triclosan-coated PDS (TCS) or plain PDS. Post-operative wound infection rates were compared.
SSI occurred in three of the 93 patients (3.2%), two of these occurred in the plain suture group, while one occurred in the TCS group (4.2% vs. 2.2%, = 0). All three SSIs were superficial. was the predominant organism isolated in the infected wounds.
The use of triclosan-coated polydioxanone for fascia closure in open appendectomy did not significantly affect the rate or severity of SSI. Further studies, perhaps evaluating the use of TCS in a different anatomical plane or complicated appendicitis are recommended.
多年来,人们一直对外科手术部位感染(SSI)保持关注,因为其发生可能会破坏手术的整体成功。抗菌缝线的使用与SSI的减少有关,但其在开放性阑尾切除术中的作用尚未得到评估。
本研究比较了用三氯生涂层聚二氧六环酮(PDS)和普通PDS进行筋膜缝合对阑尾切除术后伤口SSI的影响。
93例因单纯性急性阑尾炎接受开放性阑尾切除术的连续患者被随机分为两组,分别用三氯生涂层PDS(TCS)或普通PDS进行筋膜缝合。比较术后伤口感染率。
93例患者中有3例发生SSI(3.2%),其中2例发生在普通缝线组,1例发生在TCS组(4.2%对2.2%,P = 0)。所有3例SSI均为浅表感染。在感染伤口中分离出的主要病原体是[未提及具体病原体名称]。
在开放性阑尾切除术中使用三氯生涂层聚二氧六环酮进行筋膜缝合对SSI的发生率或严重程度没有显著影响。建议进行进一步研究,或许可以评估在不同解剖层面或复杂性阑尾炎中使用TCS的情况。