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深度部分线性 Cox 模型用于当前状态数据。

Deep partially linear cox model for current status data.

机构信息

School of Statistics, Beijing Normal University, Beijing 100875, China.

Department of Applied Mathematics, The Hong Kong Polytechnic University, Hong Kong, China.

出版信息

Biometrics. 2024 Mar 27;80(2). doi: 10.1093/biomtc/ujae024.

Abstract

Deep learning has continuously attained huge success in diverse fields, while its application to survival data analysis remains limited and deserves further exploration. For the analysis of current status data, a deep partially linear Cox model is proposed to circumvent the curse of dimensionality. Modeling flexibility is attained by using deep neural networks (DNNs) to accommodate nonlinear covariate effects and monotone splines to approximate the baseline cumulative hazard function. We establish the convergence rate of the proposed maximum likelihood estimators. Moreover, we derive that the finite-dimensional estimator for treatment covariate effects is $\sqrt{n}$-consistent, asymptotically normal, and attains semiparametric efficiency. Finally, we demonstrate the performance of our procedures through extensive simulation studies and application to real-world data on news popularity.

摘要

深度学习在各个领域不断取得巨大成功,但其在生存数据分析中的应用仍有限,值得进一步探索。对于现状数据分析,提出了一种深度部分线性 Cox 模型来规避维度诅咒。通过使用深度神经网络(DNN)来适应非线性协变量效应和单调样本来近似基线累积风险函数,从而获得建模灵活性。我们建立了所提出的最大似然估计量的收敛速度。此外,我们推导出治疗协变量效应的有限维估计量是 n 次一致的、渐近正态的,并达到半参数效率。最后,我们通过广泛的模拟研究和对新闻流行度的实际数据的应用来展示我们方法的性能。

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