Olshansky S Jay, Kirkland James L
School of Public Health, University of Illinois at Chicago, Chicago, Illinois 60612, USA
Department of Physiology and Biomedical Engineering, Division of General Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Cold Spring Harb Perspect Med. 2024 Aug 1;14(8):a041725. doi: 10.1101/cshperspect.a041725.
Why we age and whether our lifespan can be extended have intrigued scientists for centuries. Meanwhile public health advances mean humanity is having to confront the realities of an aging and increasingly frail population. The nascent field of geroscience offers hope that healthspan not just lifespan can be extended. It has spawned a vibrant scientific community that includes researchers studying fundamental biology, translational approaches, economics, and research funding. The knowledge gained from work in this area has the potential to influence the lives of most people alive today.
几个世纪以来,我们为何会衰老以及寿命能否延长一直吸引着科学家们。与此同时,公共卫生的进步意味着人类不得不面对人口老龄化且日益脆弱这一现实。新兴的老年科学领域带来了希望,即不仅寿命,健康寿命也可以延长。它催生了一个充满活力的科学界,其中包括研究基础生物学、转化方法、经济学和研究资金的研究人员。从这一领域的工作中获得的知识有可能影响当今大多数在世之人的生活。