Department of Physiology, Faculty of Medicine, The National Ribat University, Khartoum, Sudan.
Department of Physiology, Faculty of Medicine, University of Dongola, Dongola, Sudan.
BMC Res Notes. 2024 Apr 2;17(1):99. doi: 10.1186/s13104-024-06754-3.
A complete blood count (CBC) analysis is one of the most common conventional blood tests that physicians frequently prescribe.
of this study was to determine the reference intervals (RIs) of CBC parameters in the population of healthy adults living in the western Sudan region.
A cross-sectional study of healthy people residing in the western area of Sudan was carried out. We assessed the CBC RIs in samples taken from 153 individuals using an automated haematology analyser (Sysmex KX-21) and a modified Box-Cox transformation procedure to transform the data into a Gaussian distribution after eliminating outliers using the Dixon method. IBM SPSS Statistics version 25 was used to analyse the data, and t tests were employed to examine variations in the mean CBC parameters according to sex and age. P was considered significant at ≤ 0.05.
Beyond all the other measured values, the only CBC parameters that significantly differed between the sexes were haemoglobin (HGB) and white blood cell (WBC) counts. Women were found to experience more WBC counts than men did. However, they have less HGB RIs.The male participants in our study exhibited lower WBC count RIs, a significantly lower limit, and a greater upper limit of platelet RIs than did the individuals from other nations.
Compared with males, females had higher platelet and WBC counts and lower HGB.
全血细胞计数（CBC）分析是医生经常开的最常见的常规血液检查之一。
本研究旨在确定居住在苏丹西部地区的健康成年人人群中 CBC 参数的参考区间（RI）。
对居住在苏丹西部地区的健康人群进行了横断面研究。我们使用自动血液分析仪（Sysmex KX-21）评估了 153 个人的 CBC RI，并使用修改后的 Box-Cox 转换过程对数据进行转换，在使用 Dixon 方法消除离群值后将数据转换为高斯分布。使用 IBM SPSS Statistics 版本 25 分析数据，并使用 t 检验检查根据性别和年龄的平均 CBC 参数的变化。P 值≤0.05 被认为具有统计学意义。
除了所有其他测量值外，性别之间唯一显著不同的 CBC 参数是血红蛋白（HGB）和白细胞（WBC）计数。女性的 WBC 计数高于男性。然而，她们的 HGB RI 较低。与其他国家的参与者相比，我们研究中的男性参与者的 WBC 计数 RI 较低，下限显著降低，血小板 RI 的上限更高。
与男性相比，女性的血小板和 WBC 计数较高，HGB 较低。
