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基于鼻内镜检查的新型分级系统:我们对650例毛霉菌病病例的经验。

Novel Grading System Based on Nasal Endoscopy: Our Experience with 650 Mucormycosis Cases.

作者信息

Sharma Anshul, Godha Surbhi, Verma Jagram, Bhalot Lokesh, Gupta Yamini, Mundra R K

机构信息

Department of Otorhinolaryngology, Gandhi Medical College, Bhopal, MP India.

Department of Otorhinolaryngology, M.G.M Medical College, Indore, MP India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Apr;76(2):1667-1673. doi: 10.1007/s12070-023-04380-2. Epub 2023 Dec 16.

DOI:10.1007/s12070-023-04380-2
PMID:38566709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10982223/
Abstract

Rhinocerebralmucormycosis, is a progressive fungal invasion of a hard palate, paranasal sinuses, orbit, and brain. Post covid the huge number of mucor cases reported in our institute. To combat them a uniform assessment scale was needed as multiple healthcare workers were involved. Thus, a novel linear grading system on nasal endoscopy was developed for the early management of patients to prevent morbidity and mortality. A Prospective study of 650 patients in Epidemic duration from April to June 2021 in a tertiary health center, Central India. Patients subjected to Nasal Endoscopy with 0degree 4 mm Telescope and classified into 5 categories according to the severity of the disease. In a novel grading system, minimum patients were of grade 0, maximum was in Grade I. Maxillary sinus was most commonly involved. This novel grading system on nasal endoscopy makes the management of patients much easier in an epidemic, reducing human errors, morbidity, and mortality of the fulminant disease.

摘要

鼻脑型毛霉菌病是一种真菌对硬腭、鼻窦、眼眶和脑部的进行性侵袭。新冠疫情后,我们研究所报告了大量毛霉菌病例。由于涉及多名医护人员,因此需要一个统一的评估量表。于是,为了对患者进行早期管理以预防发病和死亡,开发了一种新型的鼻内镜线性分级系统。在印度中部的一家三级医疗中心对2021年4月至6月疫情期间的650名患者进行了一项前瞻性研究。患者使用0度4毫米的鼻内镜进行检查,并根据疾病严重程度分为5类。在这个新型分级系统中,0级患者最少,I级患者最多。上颌窦是最常受累的部位。这种新型的鼻内镜分级系统使疫情期间患者的管理更加容易,减少了人为错误、发病率和暴发性疾病的死亡率。

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本文引用的文献

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Mucormycosis in COVID-19: A systematic review of cases reported worldwide and in India.COVID-19 相关毛霉菌病:全球及印度病例报告的系统综述。
Diabetes Metab Syndr. 2021 Jul-Aug;15(4):102146. doi: 10.1016/j.dsx.2021.05.019. Epub 2021 May 21.
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Rhino-Orbital Mucormycosis Associated With COVID-19.与新型冠状病毒肺炎相关的鼻眶毛霉病
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Invasive fungal diseases during COVID-19: We should be prepared.2019冠状病毒病期间的侵袭性真菌病:我们应做好准备。
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Rhinocerebrocutaneous mucormycosis caused by Mucor species: A rare causation.由毛霉属物种引起的鼻脑皮肤毛霉病:一种罕见病因。
Indian Dermatol Online J. 2015 May-Jun;6(3):189-92. doi: 10.4103/2229-5178.156393.
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The "Black Turbinate" sign: An early MR imaging finding of nasal mucormycosis.“黑鼻甲”征:鼻腔毛霉菌病的早期 MRI 影像学表现。
AJNR Am J Neuroradiol. 2010 Apr;31(4):771-4. doi: 10.3174/ajnr.A1808. Epub 2009 Nov 26.
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A higher-level phylogenetic classification of the Fungi.真菌的高级系统发育分类
Mycol Res. 2007 May;111(Pt 5):509-47. doi: 10.1016/j.mycres.2007.03.004. Epub 2007 Mar 13.
10
Disseminated mucormycosis in haematological patients: CT and MRI findings with pathological correlation.血液系统疾病患者的播散性毛霉菌病:CT和MRI表现及其与病理的相关性
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