Garlapati Komali, Chavva Sunanda, Vaddeswarupu Rahul Marshal, Surampudi Jyotsna
Department of Oral Medicine and Radiology, Room No. 1, Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre, Road No. 5, Kamalanagar, Dilsukhnagar, Hyderabad, Andhra Pradesh 500060, India.
Department of Oral Medicine and Radiology, Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre, Hyderabad, Andhra Pradesh 500060, India.
Case Rep Dent. 2014;2014:465919. doi: 10.1155/2014/465919. Epub 2014 Jan 9.
Mucormycosis is an opportunistic fulminant fungal infection, which has the ability to cause significant morbidity and frequently mortality in the susceptible patient. Common predisposing factors include diabetes mellitus and immunosuppression. The infection begins in the nose and paranasal sinuses due to inhalation of fungal spores. The fungus invades the arteries leading to thrombosis that subsequently causes necrosis of the tissue. The infection can spread to orbital and intracranial structures either by direct invasion or through the blood vessels. Here we describe a case of mucormycosis of maxillary antrum extending to ethmoidal and frontal sinus and also causing necrosis of left maxilla in an uncontrolled diabetic individual to emphasize early diagnosis and treatment of this fatal fungal infection.
毛霉病是一种机会性暴发性真菌感染，能够在易感患者中导致严重发病甚至常常死亡。常见的诱发因素包括糖尿病和免疫抑制。感染因吸入真菌孢子而始于鼻腔和鼻窦。真菌侵入动脉导致血栓形成，随后引起组织坏死。感染可通过直接侵袭或经血管扩散至眼眶和颅内结构。在此，我们描述一例上颌窦毛霉病病例，该病例蔓延至筛窦和额窦，并导致一名血糖控制不佳的糖尿病患者左侧上颌骨坏死，以强调对这种致命真菌感染的早期诊断和治疗。
