• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

比较罗哌卡因与布比卡因扁桃体窝扁桃体切除术中浸润的效果。

To Compare the Effects of Post-tonsillectomy Intra-operative Infiltration of Ropivacaine Versus Bupivacaine in Tonsillar Fossa.

作者信息

Nitin B, Gupta Manish

机构信息

Department of ENT and Head Neck Surgery, Maharishi Markandeshwar College of Medical Sciences and Research, Ambala, Haryana India.

Department of ENT and Head Neck Surgery, Gian Sagar Hospital and Medical College, Banur Rajpura, Punjab India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Apr;76(2):1805-1818. doi: 10.1007/s12070-023-04417-6. Epub 2023 Dec 23.

DOI:10.1007/s12070-023-04417-6
PMID:38566710
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10982168/
Abstract

Tonsillectomy is one of the most common surgical procedures practiced in Otorhinolaryngology. A significant obstacle for the speedy and smooth recovery is early post- operative pain. Pain leads to negative outcomes such as poor intake, tachycardia, anxiety, delayed wound healing and insomnia. Aim to assess and compare the effect of post-incisional infiltration of 0.75% Ropivacaine v/s 0.5% Bupivacaine on post tonsillectomy pain, the on start of oral intake and stay in hospital and to investigate any complications that can arise due to infiltration of the said drugs. 60 Patients above the age of 5 years were posted for tonsillectomy or adenotonsillectomy under general anesthesia. Patients were blinded about the group in which they will be enrolled. Group A received Inj. ropivacaine (0.75%) 2 ml and Group B: received Inj. Bupivacaine (0.50%) 2 ml in each fossa. After surgery, no analgesics were given & patients were observed for the intensity of post-operative pain in the immediate post-operative period, at 2, 4, 6, 12, 24, 48 h and further if not discharged using VISUAL ANALOGUE SCORE (VAS) and VERBAL RATING SCALE(VRS). Post-operative pain assessment was done using VAS and VRS at 2nd, 4th, 6th, 12th, 24th and 48th hour which was found to be lower in Group 'A'. Patients in Group 'A' also started their oral intake sooner, had lesser hospitalization days than group 'B' patients. Longer time for Rescue analgesic and reduced total dose of analgesic required was seen in Group A compared to Group B. This comparative study on Post-incisional infiltration of 2 ml 0.75% Ropivacaine v/s 2 ml 0.5% Bupivacaine has shown that Ropivacaine is a more effective drug in reducing post-operative pain in comparison to Bupivacaine, proven statistically.

摘要

扁桃体切除术是耳鼻喉科最常见的外科手术之一。术后早期疼痛是快速顺利康复的一个重大障碍。疼痛会导致诸如摄入不足、心动过速、焦虑、伤口愈合延迟和失眠等负面结果。目的是评估和比较0.75%罗哌卡因与0.5%布比卡因切口浸润对扁桃体切除术后疼痛、开始经口进食时间和住院时间的影响,并调查因上述药物浸润可能出现的任何并发症。60名5岁以上患者在全身麻醉下接受扁桃体切除术或腺样体扁桃体切除术。患者对自己将被纳入的组别不知情。A组在每个窝内注射2毫升0.75%罗哌卡因注射液,B组在每个窝内注射2毫升0.5%布比卡因注射液。手术后,未给予镇痛剂,并使用视觉模拟评分法(VAS)和语言评定量表(VRS)在术后即刻、2、4、6、12、24、48小时以及若未出院则进一步观察患者术后疼痛强度。在第2、4、6、12、24和48小时使用VAS和VRS进行术后疼痛评估,发现“A组”疼痛程度较低。“A组”患者也更早开始经口进食,住院天数比“B组”患者少。与“B组”相比,“A组”患者使用补救镇痛剂的时间更长,所需镇痛剂的总剂量减少。这项关于2毫升0.75%罗哌卡因与2毫升0.5%布比卡因切口浸润的对比研究表明,与布比卡因相比,罗哌卡因在减轻术后疼痛方面是一种更有效的药物,经统计学验证。

相似文献

1
To Compare the Effects of Post-tonsillectomy Intra-operative Infiltration of Ropivacaine Versus Bupivacaine in Tonsillar Fossa.比较罗哌卡因与布比卡因扁桃体窝扁桃体切除术中浸润的效果。
Indian J Otolaryngol Head Neck Surg. 2024 Apr;76(2):1805-1818. doi: 10.1007/s12070-023-04417-6. Epub 2023 Dec 23.
2
Role of Pre-incisional Bupivacaine Infiltration in Post-tonsillectomy Analgesia.切开前布比卡因浸润在扁桃体切除术后镇痛中的作用。
Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):5296-5300. doi: 10.1007/s12070-020-02252-7. Epub 2020 Nov 5.
3
Peritonsillar dexamethasone-bupivacaine vs. bupivacaine infiltration for post-tonsillectomy pain relief in children: a randomized, double-blind, controlled study.儿童扁桃体切除术后疼痛缓解:地塞米松-布比卡因与布比卡因扁桃体周浸润的随机、双盲、对照研究
Eur Arch Otorhinolaryngol. 2019 Jul;276(7):2081-2089. doi: 10.1007/s00405-019-05472-y. Epub 2019 May 21.
4
Comparison of Ropivacaine and Bupivacaine in Intraperitoneal Instillation for Postoperative Analgesia in Laparoscopic Cholecystectomy: A Randomized Controlled Trial.罗哌卡因与布比卡因用于腹腔镜胆囊切除术后腹腔内滴注镇痛的比较:一项随机对照试验
Cureus. 2024 Nov 6;16(11):e73167. doi: 10.7759/cureus.73167. eCollection 2024 Nov.
5
Comparison of ropivacaine, bupivacaine and lidocaine in the management of post-tonsillectomy pain.罗哌卡因、布比卡因和利多卡因用于扁桃体切除术后疼痛管理的比较。
Int J Pediatr Otorhinolaryngol. 2012 Dec;76(12):1831-4. doi: 10.1016/j.ijporl.2012.09.011. Epub 2012 Sep 27.
6
Ultrasound guided peritubal infiltration of 0.25% Bupivacaine versus 0.25% Ropivacaine for postoperative pain relief after percutaneous nephrolithotomy: A prospective double blind randomized study.超声引导下0.25%布比卡因与0.25%罗哌卡因用于经皮肾镜取石术后疼痛缓解的输卵管周围浸润:一项前瞻性双盲随机研究。
Indian J Anaesth. 2014 May;58(3):293-7. doi: 10.4103/0019-5049.135040.
7
Comparison of bupivacaine and ropivacaine on postoperative pain after tonsillectomy in paediatric patients.布比卡因与罗哌卡因对小儿扁桃体切除术后疼痛的比较。
Int J Pediatr Otorhinolaryngol. 2007 Jan;71(1):83-7. doi: 10.1016/j.ijporl.2006.09.005. Epub 2006 Nov 7.
8
Role of Preincisional Peritonsillar Infiltration of Bupivacaine in Postoperative Pain Relief in Tonsillectomy Patients.布比卡因术前扁桃体周围浸润在扁桃体切除术后疼痛缓解中的作用。
Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):610-613. doi: 10.1007/s12070-018-1436-y. Epub 2018 Jun 21.
9
Comparative Study of Postoperative Pain Relief Using Preincisional Versus Postincisional Infiltration With 0.25% Bupivacaine in Abdominal Hysterectomy Under General Anesthesia.全身麻醉下腹部子宫切除术中采用术前与术后 0.25%布比卡因切口浸润进行术后疼痛缓解的比较研究
Anesth Essays Res. 2021 Jul-Sep;15(3):332-337. doi: 10.4103/aer.aer_104_21. Epub 2022 Feb 14.
10
[Pre-emptive analgesia with ropivacaine in adult tonsillectomy].
Anaesthesist. 1999 Jun;48(6):373-8. doi: 10.1007/s001010050715.

本文引用的文献

1
Basic pharmacology of local anaesthetics.局部麻醉药的基础药理学
BJA Educ. 2020 Feb;20(2):34-41. doi: 10.1016/j.bjae.2019.10.002. Epub 2019 Dec 4.
2
Local and regional anaesthesia in dogs and cats: Overview of concepts and drugs (Part 1).犬猫局部和区域麻醉:概念和药物概述(第一部分)。
Vet Med Sci. 2020 May;6(2):209-217. doi: 10.1002/vms3.219. Epub 2020 Jan 21.
3
Comparison of ropivacaine, bupivacaine and lidocaine in the management of post-tonsillectomy pain.罗哌卡因、布比卡因和利多卡因用于扁桃体切除术后疼痛管理的比较。
Int J Pediatr Otorhinolaryngol. 2012 Dec;76(12):1831-4. doi: 10.1016/j.ijporl.2012.09.011. Epub 2012 Sep 27.
4
Clinical practice guideline: tonsillectomy in children.临床实践指南:儿童扁桃体切除术。
Otolaryngol Head Neck Surg. 2011 Jan;144(1 Suppl):S1-30. doi: 10.1177/0194599810389949.
5
Comparison of peritonsillar levobupivacaine and bupivacaine infiltration for post-tonsillectomy pain relief in children: placebo-controlled clinical study.儿童扁桃体切除术后疼痛缓解中,腭扁桃体周围左旋布比卡因与布比卡因浸润的比较:安慰剂对照临床研究
Int J Pediatr Otorhinolaryngol. 2011 Mar;75(3):322-6. doi: 10.1016/j.ijporl.2010.11.015. Epub 2010 Dec 18.
6
High-dose ropivacaine versus bupivacaine for posttonsillectomy pain relief in adults.高剂量罗哌卡因与布比卡因用于成人扁桃体切除术后疼痛缓解的比较
J Otolaryngol Head Neck Surg. 2008 Dec;37(6):836-43.
7
Comparison of bupivacaine and ropivacaine on postoperative pain after tonsillectomy in paediatric patients.布比卡因与罗哌卡因对小儿扁桃体切除术后疼痛的比较。
Int J Pediatr Otorhinolaryngol. 2007 Jan;71(1):83-7. doi: 10.1016/j.ijporl.2006.09.005. Epub 2006 Nov 7.
8
Preincisional infiltration of tonsils with ropivacaine in post-tonsillectomy pain relief: double-blind, randomized, placebo-controlled intraindividual study.罗哌卡因扁桃体切除术前浸润用于减轻扁桃体切除术后疼痛:双盲、随机、安慰剂对照个体内研究。
J Otolaryngol. 2006 Jun;35(3):167-72.
9
Ropivacaine compared to bupivacaine for post-tonsillectomy pain relief in children: a randomized controlled study.罗哌卡因与布比卡因用于儿童扁桃体切除术后疼痛缓解的比较:一项随机对照研究。
Int J Pediatr Otorhinolaryngol. 2006 Jul;70(7):1169-73. doi: 10.1016/j.ijporl.2005.12.001. Epub 2006 Jan 18.
10
Effect of perioperative administration of ropivacaine with epinephrine on postoperative pediatric adenotonsillectomy recovery.围手术期给予罗哌卡因加肾上腺素对小儿扁桃体腺样体切除术后恢复的影响。
Arch Otolaryngol Head Neck Surg. 2004 Apr;130(4):459-64. doi: 10.1001/archotol.130.4.459.