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疱疹相关性多形红斑患者口腔健康相关生活质量的评估:一例独特病例报告

Evaluation of Oral Health-Related Quality of Life in Patient with Herpes-Associated Erythema Multiforme: A Unique Case Report.

作者信息

Bakti Fitrah Utari, Dewi Tenny Setiani

机构信息

Oral Medicine Residency, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia.

Oral Medicine Department, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia.

出版信息

Int Med Case Rep J. 2024 Mar 29;17:253-259. doi: 10.2147/IMCRJ.S456301. eCollection 2024.

DOI:10.2147/IMCRJ.S456301
PMID:38566932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10986623/
Abstract

INTRODUCTION

Erythema multiforme (EM) is an acute mucocutaneous hypersensitivity reaction with various etiological factors, including herpes simplex virus type 1 (HSV-1) infection, known as herpes-associated erythema multiforme (HAEM). Oral health-related quality of life (OHRQoL) is a multidimensional concept of biopsychosocial aspects related to oral health. OHRQol contains information for patient-centered treatment plan development. The OHRQoL measurement instrument widely used by clinicians is the oral health impact profile-14 (OHIP-14). This case report aimed to evaluate OHRQoL in HAEM patient, which only manifests on the lips and oral cavity.

CASE

A 25-year-old male patient came to the Department of Oral Medicine with the chief complaint of painful canker sores on the lips. Extra-oral examination revealed serosanguineous crusts on the lips that were painful and easily bleed. Intra-oral examination showed diffused and painful irregular erythematous lesions on the upper and lower labial mucosa. The anti-HSV1 IgG test was positive. The patient was diagnosed with HAEM.

CASE MANAGEMENT

Pharmacological therapy included triamcinolone acetonide 0.1% in orabase, acyclovir tablets, multivitamins, and 0.9% NaCl. Non-pharmacological therapy included advice on maintaining good oral hygiene, avoiding spicy and sour foods, and breaking the bad habit of licking the lips.

CONCLUSION

The patient's physical, psychological, and social conditions showed improvement and returned to normal after 7 days of treatment. In conclusion, oral health is an important factor that can improve the quality of life of HAEM patient.

摘要

引言

多形红斑(EM)是一种急性黏膜皮肤超敏反应,病因多样,包括1型单纯疱疹病毒(HSV-1)感染,即疱疹相关性多形红斑(HAEM)。口腔健康相关生活质量(OHRQoL)是一个与口腔健康相关的生物心理社会方面的多维概念。OHRQoL包含以患者为中心的治疗计划制定所需的信息。临床医生广泛使用的OHRQoL测量工具是口腔健康影响程度量表-14(OHIP-14)。本病例报告旨在评估仅在唇部和口腔出现症状的HAEM患者的OHRQoL。

病例

一名25岁男性患者因唇部疼痛性口腔溃疡为主诉前来口腔内科就诊。口腔外检查发现唇部有浆液血性痂皮,疼痛且易出血。口腔内检查显示上下唇黏膜有弥漫性、疼痛性不规则红斑病变。抗HSV1 IgG检测呈阳性。该患者被诊断为HAEM。

病例管理

药物治疗包括0.1%曲安奈德口腔糊剂、阿昔洛韦片、多种维生素和0.9%氯化钠。非药物治疗包括保持良好口腔卫生、避免辛辣和酸味食物以及改掉舔唇的不良习惯的建议。

结论

经过7天治疗,患者的身体、心理和社会状况有所改善并恢复正常。总之,口腔健康是改善HAEM患者生活质量的重要因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffcd/10986623/e91b110da810/IMCRJ-17-253-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffcd/10986623/930f0b4056e9/IMCRJ-17-253-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffcd/10986623/e91b110da810/IMCRJ-17-253-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffcd/10986623/930f0b4056e9/IMCRJ-17-253-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffcd/10986623/e91b110da810/IMCRJ-17-253-g0002.jpg

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HSV-associated erythema multiforme in a patient after hematopoietic stem cell transplantation.造血干细胞移植后患者的单纯疱疹病毒相关多形红斑。
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