Department of Internal Medicine/Nephrology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Department of Internal Medicine/Endocrinology, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.
Int J Med Robot. 2024 Apr;20(2):e2630. doi: 10.1002/rcs.2630.
We investigated the rates of acute kidney injury (AKI) post robot-assisted laparoscopic prostatectomy (RALP).
A comprehensive search was conducted to identify studies that reported the rates of AKI post-RALP. A random effects model was used, and the pooled rates of AKI were calculated.
We identified 10 studies with 60,937 patients to be included. The mean age was 65.1 years. The mean anaesthesia time was 234.3 min (95% CI: 177.8-290.9). The mean operation time was 212.2 min (95% CI: 188.7-235.6). The mean estimated blood loss was 314.1 mL (95% CI: 153-475.3). The mean intraoperative IV fluids administered were 1985 mL (95% CI: 1516.3-2453.7). The pooled rate of AKI post RALP was 7.2% (95% CI 19-23.9).
The rates of AKI after RALP are significant. Further studies are needed to detect the risk factors for AKI and to determine the rates of chronic kidney disease post-RALP.
我们研究了机器人辅助腹腔镜前列腺切除术（RALP）后急性肾损伤（AKI）的发生率。
进行了全面检索，以确定报告 RALP 后 AKI 发生率的研究。使用随机效应模型计算 AKI 的汇总发生率。
我们确定了 10 项研究，共纳入 60937 例患者。平均年龄为 65.1 岁。平均麻醉时间为 234.3 分钟（95%置信区间：177.8-290.9）。平均手术时间为 212.2 分钟（95%置信区间：188.7-235.6）。平均估计出血量为 314.1 毫升（95%置信区间：153-475.3）。术中平均输注的静脉液体量为 1985 毫升（95%置信区间：1516.3-2453.7）。RALP 后 AKI 的汇总发生率为 7.2%（95%置信区间 19-23.9）。
RALP 后 AKI 的发生率较高。需要进一步研究以检测 AKI 的危险因素，并确定 RALP 后慢性肾脏病的发生率。
